Propamocarb

Base Information

• Chemical Name: Propamocarb
• CAS No.: 24579-73-5
• Molecular Formula: C9H20N2O2
• Molecular Weight: 188.27
• Hs Code.: 29241990
• European Community (EC) Number: 607-406-2
• UNII: 8HLL7N9UWO
• DSSTox Substance ID: DTXSID1040295
• Nikkaji Number: J20.381E
• Wikipedia: Propamocarb
• Wikidata: Q1927058
• ChEMBL ID: CHEMBL1907431
• Mol file: 24579-73-5.mol

Synonyms:Previcur;propamocarb;propamocarb monohydrochloride;propyl(3-(dimethylamino)propyl)carbamate monohydrochloride

Chemical Property of Propamocarb

Chemical Property:

• Appearance/Colour: colourless liquid
• Vapor Pressure: 0.015mmHg at 25°C
• Melting Point: 45-55ºC
• Refractive Index: 1.449
• Boiling Point: 272.3 °C at 760 mmHg
• PKA: 12.73±0.46(Predicted)
• Flash Point: 118.5 °C
• PSA: 41.57000
• Density: 0.957 g/cm³
• LogP: 1.46520
• Storage Temp.: APPROX 4°C
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 188.152477885
• Heavy Atom Count: 13
• Complexity: 138

Purity/Quality:

99.9% ^*data from raw suppliers

Propamocarb ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCOC(=O)NCCCN(C)C
• Uses: Carbamate fungicide used in the agriculture industry

Technology Process of Propamocarb

There total 3 articles about Propamocarb which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.7%

propan-1-ol (71-23-8) + carbon monoxide (201230-82-2) + 1-amino-3-(dimethylamino)propane (109-55-7) → propamocarb (24579-73-5)

Guidance literature:

propan-1-ol; 1-amino-3-(dimethylamino)propane; With sodium iodide; palladium dichloride; at 125 ℃; for 1h; Autoclave; Inert atmosphere;

carbon monoxide; With oxygen; under 30003 Torr; Concentration; Pressure; Reagent/catalyst; Autoclave;

Reference yield: 75.6%

propan-1-ol (71-23-8) + carbon monoxide (201230-82-2) + 1-amino-3-(dimethylamino)propane (109-55-7) → propamocarb (24579-73-5) + urea (57-13-6)

Guidance literature:

With oxygen; N,N-dimethyl-formamide; sodium iodide; palladium dichloride; at 125 ℃; for 2h; under 30003 Torr; Pressure; Reagent/catalyst; Autoclave; Inert atmosphere;

Reference yield:

→ propamocarb (24579-73-5)

Guidance literature:

upstream raw materials:

propan-1-ol

carbon monoxide

1-amino-3-(dimethylamino)propane

Downstream raw materials:

propamocarb hydrochloride

Refernces

• 1、 -. "Substituted imide derivatives". . . Retrieved 2008/06/13.
• 2、 -. "2-and 2,5-substituted phenylketoenols". . . Retrieved 2008/06/13.