1-NAPHTHALENEBORONIC ACID NEOPENTYL GLYCOL CYCLIC ESTER

Base Information

• Chemical Name: 1-NAPHTHALENEBORONIC ACID NEOPENTYL GLYCOL CYCLIC ESTER
• CAS No.: 22871-77-8
• Molecular Formula: C15H17BO2
• Molecular Weight: 240.11
• Hs Code.: 2934999090
• Mol file: 22871-77-8.mol

Synonyms:1-Naphthaleneboronic acid neopentyl glycol ester;1-Naphthaleneboronic Acid Neopentyl Glycol Cyclic Ester;

Chemical Property of 1-NAPHTHALENEBORONIC ACID NEOPENTYL GLYCOL CYCLIC ESTER

Chemical Property:

• Vapor Pressure: 7.26E-06mmHg at 25°C
• Melting Point: 67-69oC
• Boiling Point: 387.6oC at 760 mmHg
• Flash Point: 188.2oC
• PSA: 18.46000
• Density: 1.08g/cm3
• LogP: 2.60800
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

5,5-Dimethyl-2-(naphthalen-1-yl)-1,3,2-dioxaborinane ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-NAPHTHALENEBORONIC ACID NEOPENTYL GLYCOL CYCLIC ESTER

There total 26 articles about 1-NAPHTHALENEBORONIC ACID NEOPENTYL GLYCOL CYCLIC ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

1-(4-fluorophenyl)naphthalene (572-52-1) + 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane (201733-56-4) → 5,5-dimethyl-2-(naphthalen-1-yl)-1,3,2-dioxaborinane (22871-77-8)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; sodium phenoxide; tricyclohexylphosphine; In tetrahydrofuran; at 110 ℃; for 15h; Schlenk technique; Inert atmosphere; Glovebox;

DOI:10.1021/jacs.5b08103

Reference yield: 92.0%

1-Naphthylboronic acid (13922-41-3) + 2,2-Dimethyl-1,3-propanediol (126-30-7) → 5,5-dimethyl-2-(naphthalen-1-yl)-1,3,2-dioxaborinane (22871-77-8)

Guidance literature:

With calcium chloride; In tetrahydrofuran; at 20 ℃; for 0.5h;

DOI:10.1021/acs.joc.6b02623

Reference yield: 84.0%

1-Methoxynaphthalene (2216-69-5) + 2-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane (201733-56-4) → 5,5-dimethyl-2-(naphthalen-1-yl)-1,3,2-dioxaborinane (22871-77-8)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; sodium formate; tricyclohexylphosphine; In toluene; at 95 ℃; for 15h; Inert atmosphere;

DOI:10.1021/jacs.5b03955

upstream raw materials:

tris(1-naphthyl)stilbane

2,2-Dimethyl-1,3-propanediol

1-Naphthylboronic acid

methanol

Downstream raw materials:

1-(4-chlorophenyl)naphthalene

1-(2,6-dimethylphenyl)naphthalene

1-phenylnaphthalene