3-Isopropylcyclohexanone

Base Information

• Chemical Name: 3-Isopropylcyclohexanone
• CAS No.: 23396-36-3
• Molecular Formula: C9H16O
• Molecular Weight: 140.225
• Hs Code.: 2914299000
• Mol file: 23396-36-3.mol

Synonyms:3-Isopropyl-cyclohexanon;3-isopropylcyclohexanone;Cyclohexanone,3-(1-methylethyl);3-isopropyl-cyclohexan-1-one;

Chemical Property of 3-Isopropylcyclohexanone

Chemical Property:

• PSA: 17.07000
• LogP: 2.40170

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Isopropylcyclohexanone

There total 49 articles about 3-Isopropylcyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cyclohexenone (930-68-7) + isopropylmagnesium chloride (1068-55-9) → 3-isopropylcyclohexanone (23396-36-3)

Guidance literature:

isopropylmagnesium chloride; With copper(l) chloride; In tetrahydrofuran; at -78 ℃; for 1.5h; Inert atmosphere;

cyclohexenone; With chloro-trimethyl-silane; In tetrahydrofuran; at -78 ℃; for 20h; Inert atmosphere;

DOI:10.1002/chem.201805837

Reference yield: 97.0%

cyclohexenone (930-68-7) + isopropylmagnesium bromide (920-39-8) → 3-isopropylcyclohexanone (23396-36-3)

Guidance literature:

With n-butyllithium; zinc(II) chloride; (2S,2'S)-2-hydroxymethyl-1-<(1-methylpyrrolidine-2-yl)methyl>pyrrolidine; In tetrahydrofuran; at -90 ℃; for 0.25h;

DOI:10.1021/jo00300a039

Reference yield: 95.0%

2-iodo-propane (75-30-9) + cyclohexenone (930-68-7) → 3-isopropylcyclohexanone (23396-36-3)

Guidance literature:

With zinc copper; In ethanol; water; Ambient temperature; under sonication;;

DOI:10.1016/S0040-4039(00)82870-1

upstream raw materials:

5-isopropyl-1,3-cyclohexanedione

3-isopropyl-1-cyclohexanol

cyclohexenone

isopropylmagnesium bromide

Downstream raw materials:

(3S)-3-isopropylcyclohexanone

3-Isopropyl-cyclohexanon-cyanhydrin

(+-)-3-isopropyl-adipic acid

acetic acid