4-Chloro-N,N-dimethylpyrimidin-2-amine

Base Information

Chemical Name:4-Chloro-N,N-dimethylpyrimidin-2-amine
CAS No.:23631-02-9
Molecular Formula:C6H8ClN3
Molecular Weight:157.603
Hs Code.:2933599090
European Community (EC) Number:847-982-4
Mol file:23631-02-9.mol

Synonyms:4-Chloro-N,N-dimethylpyrimidin-2-amine;23631-02-9;(4-Chloro-pyrimidin-2-yl)-dimethyl-amine;2-Pyrimidinamine, 4-chloro-N,N-dimethyl-;4-chloro-n,n-dimethyl-2-pyrimidinamine;(4-Chloropyrimidin-2-yl)dimethylamine;SCHEMBL4262005;CJKPZNGEVQSIND-UHFFFAOYSA-N;4-chloro-2-dimethylaminopyrimidine;YAA63102;MFCD00234092;AKOS010519089;AB05128;(4-Chloro-pyrimidin-2-yl)dimethylamine;AM100555;AS-19953;DB-324971;CS-0054917;EN300-81635;F11794;A878182

Suppliers and Price of 4-Chloro-N,N-dimethylpyrimidin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Chloro-N,N-dimethylpyrimidin-2-amine
10mg
$ 45.00

Medical Isotopes, Inc.
4-chloro-N,N-dimethylpyrimidin-2-amine 97%
1 g
$ 850.00

Crysdot
4-Chloro-N,N-dimethylpyrimidin-2-amine 97%
1g
$ 392.00

Chemenu
4-chloro-N,N-dimethylpyrimidin-2-amine 97%
1g
$ 486.00

Ambeed
4-Chloro-N,N-dimethylpyrimidin-2-amine 97%
1g
$ 292.00

AK Scientific
(4-Chloro-pyrimidin-2-yl)-dimethyl-amine
100mg
$ 80.00

Total 10 raw suppliers

Chemical Property of 4-Chloro-N,N-dimethylpyrimidin-2-amine

Chemical Property:

Boiling Point:248.9±32.0 °C(Predicted)
PKA:3.83±0.10(Predicted)
PSA：29.02000
Density:1.252±0.06 g/cm3(Predicted)
LogP:1.19600
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:157.0406750
Heavy Atom Count:10
Complexity:107

Purity/Quality:

99%, ^*data from raw suppliers

4-Chloro-N,N-dimethylpyrimidin-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=NC=CC(=N1)Cl

Technology Process of 4-Chloro-N,N-dimethylpyrimidin-2-amine

There total 2 articles about 4-Chloro-N,N-dimethylpyrimidin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 3934-20-1
2,6-Dichloropyrimidine

: 124-40-3
dimethyl amine

: 31058-81-8
2-chloro-N,N-dimethylpyrimidin-4-amine

: 23631-02-9
4-chloro-N,N-dimethylpyrimidine-2-amine

Guidance literature:: In methanol; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.6b01448

Reference yield: 55.0%

: 3934-20-1
2,6-Dichloropyrimidine

: 74-89-5
methylamine

: 31058-81-8
2-chloro-N,N-dimethylpyrimidin-4-amine

: 23631-02-9
4-chloro-N,N-dimethylpyrimidine-2-amine

Guidance literature:: In tetrahydrofuran; water; at 20 ℃; for 2h;

Reference yield:

: 23631-02-9
4-chloro-N,N-dimethylpyrimidine-2-amine

: 866648-44-4
N-(cis-4-bromo-2-trifluoromethoxy-benzyl)-cyclohexane-1,4-diamine

: N₄-(cis-4-{[4-bromo-2-(trifluoromethoxy)benzyl]-amino}cyclohexyl)-N₂,N₂-dimethylpyrimidine-2,4-diamine

Guidance literature:: 4-chloro-N,N-dimethylpyrimidine-2-amine; N-(cis-4-bromo-2-trifluoromethoxy-benzyl)-cyclohexane-1,4-diamine; In butan-1-ol; for 13h; Heating / reflux;

With sodium hydrogencarbonate; In water; butan-1-ol;