5-Chloro-2-(4-methoxyphenyl)benzofuran

Base Information

Chemical Name:5-Chloro-2-(4-methoxyphenyl)benzofuran
CAS No.:24472-98-8
Molecular Formula:C15H11ClO2
Molecular Weight:258.704
Hs Code.:
DSSTox Substance ID:DTXSID201284794
Nikkaji Number:J1.154.724I
ChEMBL ID:CHEMBL3893696

Synonyms:5-chloro-2-(4-methoxyphenyl)benzofuran;5-Chloro-2-(4-methoxy-phenyl)-benzofuran;SCHEMBL3923822;CHEMBL3893696;NWJSWPAUARLDLI-UHFFFAOYSA-N;DTXSID201284794;SKF-81733;24472-98-8

Suppliers and Price of 5-Chloro-2-(4-methoxyphenyl)benzofuran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-Chloro-2-(4-methoxyphenyl)benzofuran

Chemical Property:

XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:258.0447573
Heavy Atom Count:18
Complexity:276

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CC3=C(O2)C=CC(=C3)Cl

Technology Process of 5-Chloro-2-(4-methoxyphenyl)benzofuran

There total 21 articles about 5-Chloro-2-(4-methoxyphenyl)benzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 3462-97-3
(4-methoxybenzyl)triphenylphosphonium bromide

: 635-93-8
5-chlorosalicyclaldehyde

: 24472-98-8
5-Chloro-2-(4-methoxy-phenyl)-benzofuran

Guidance literature:: (4-methoxybenzyl)triphenylphosphonium bromide; 5-chlorosalicyclaldehyde; With potassium hydroxide; In PEG-600; at 20 ℃;

With potassium carbonate; In PEG-600; at 20 ℃; for 2 - 3h;

With iodine; In PEG-600; at 20 ℃;
DOI:10.1039/c2gc16181h

Reference yield: 85.0%

: C₁₆H₁₁ClO₄^(2-)*2Na⁽¹⁺⁾

: 24472-98-8
5-Chloro-2-(4-methoxy-phenyl)-benzofuran

Guidance literature:: With 1,10-Phenanthroline; copper(l) chloride; In dimethyl sulfoxide; at 150 ℃; Molecular sieve;
DOI:10.1039/c3ra46414h

Reference yield: 80.0%

: 71643-66-8
4-chloro-2-iodo phenol

: 768-60-5
4-methoxyphenylacetylen

: 24472-98-8
5-Chloro-2-(4-methoxy-phenyl)-benzofuran

Guidance literature:: With rac-N₂,N₂'-bis(benzyl)-1,1'-binaphthyl-2,2'-diamine; copper(II) bis(trifluoromethanesulfonate); potassium carbonate; In toluene; for 28h; Inert atmosphere; Reflux;
DOI:10.1016/j.tet.2010.01.026