Propionic acid 2-hydroxyethyl ester

Base Information

• Chemical Name: Propionic acid 2-hydroxyethyl ester
• CAS No.: 24567-27-9
• Molecular Formula: C5H10O3
• Molecular Weight: 118.133
• Hs Code.: 2915509000
• Mol file: 24567-27-9.mol

Synonyms:Propionsaeure-monoglykolester;propionic acid-(2-hydroxy-ethyl ester);glycol monopropionate;Propionsaeure-(2-hydroxy-aethylester);1,2-Ethanediol,monopropanoate;2-hydroxyethyl propionate;

Chemical Property of Propionic acid 2-hydroxyethyl ester

Chemical Property:

• Boiling Point: 90-97 °C(Press: 16 Torr)
• PKA: 13.86±0.10(Predicted)
• PSA: 77.76000
• Density: 1.054±0.06 g/cm3(Predicted)
• LogP: -0.54800

Purity/Quality:

99% ^*data from raw suppliers

2-Hydroxyethylpropionate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propionic acid 2-hydroxyethyl ester

There total 3 articles about Propionic acid 2-hydroxyethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

ethylene glycol (107-21-1) + Ethyl propionate (105-37-3,20741-13-3) → 2-hydroxyethyl propionate (24567-27-9) + ethylene glycol diproprionate (123-80-8)

Guidance literature:

Dowex 50W; In octane; at 100 ℃; for 4h;

DOI:10.1021/jo00084a043

Reference yield:

[1,3]-dioxolan-2-one (96-49-1) + ethylmagnesium bromide (925-90-6) → 3-ethylpentan-3-ol (597-49-9) + 2-hydroxyethyl propionate (24567-27-9) + pentan-3-one (96-22-0)

Guidance literature:

In tetrahydrofuran; 2-methyltetrahydrofuran; at 20 ℃; Green chemistry;

DOI:10.1002/cssc.202100262

Reference yield:

2-methoxy-2-ethyl-1,3-dioxolane (90788-52-6) → methanol (67-56-1) + 2-hydroxyethyl propionate (24567-27-9)

Guidance literature:

With HCl or phosphate buffer; water; at 25 ℃; Product distribution; Kinetics; Mechanism; rate and equilibrium constant in hydrolysis at ionic strength 0.1;

DOI:10.1021/ja00217a036

upstream raw materials:

2-methoxy-2-ethyl-1,3-dioxolane

ethylene glycol

Ethyl propionate

[1,3]-dioxolan-2-one

Downstream raw materials:

2-(((4-Nitrophenyl)sulfonyl)oxy)ethyl propionate

2-Oxo-4-(2-propionyloxy-ethoxy)-6-p-tolyl-cyclohex-3-enecarboxylic acid ethyl ester