2-(methylsulfanyl)-4-phenyl-1H-imidazole

Base Information

Chemical Name:2-(methylsulfanyl)-4-phenyl-1H-imidazole
CAS No.:25433-10-7
Molecular Formula:C10H10N2S
Molecular Weight:190.26500
Hs Code.:
DSSTox Substance ID:DTXSID90397875
Nikkaji Number:J1.443.783E
Wikidata:Q82199512
ChEMBL ID:CHEMBL3302303
Mol file:25433-10-7.mol

Synonyms:2-(methylsulfanyl)-4-phenyl-1H-imidazole;25433-10-7;2-methylsulfanyl-5-phenyl-1H-imidazole;2-(Methylthio)-4-phenyl-1H-imidazole;1H-Imidazole, 2-(methylthio)-4-phenyl-;CHEMBL3302303;DTXSID90397875;STK045354;AKOS005383931;CS-0230319;EN300-103260;Z352223348

Suppliers and Price of 2-(methylsulfanyl)-4-phenyl-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(methylsulfanyl)-4-phenyl-1H-imidazole
100mg
$ 285.00

TRC
2-(methylsulfanyl)-4-phenyl-1H-imidazole
50mg
$ 175.00

TRC
2-(methylsulfanyl)-4-phenyl-1H-imidazole
10mg
$ 45.00

AK Scientific
2-(Methylsulfanyl)-4-phenyl-1H-imidazole
250mg
$ 407.00

Total 4 raw suppliers

Chemical Property of 2-(methylsulfanyl)-4-phenyl-1H-imidazole

Chemical Property:

PSA：53.98000
LogP:2.79860
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:190.05646950
Heavy Atom Count:13
Complexity:157

Purity/Quality:

99% ^*data from raw suppliers

2-(methylsulfanyl)-4-phenyl-1H-imidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSC1=NC=C(N1)C2=CC=CC=C2

Technology Process of 2-(methylsulfanyl)-4-phenyl-1H-imidazole

There total 5 articles about 2-(methylsulfanyl)-4-phenyl-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 917-54-4
methyllithium

: 4335-28-8
2,3-diidro-6-fenilimidazo<2,1-b>tiazolo

: 25433-10-7
2-(methylthio)-4-phenyl-1H-imidazole

Guidance literature:: In tetrahydrofuran; at -78 ℃; for 1h;
DOI:10.1021/ol006302n

Reference yield: 43.0%

: 147895-43-0
S-methylisothiourea hemisulphate

: 70-11-1
α-bromoacetophenone

: 25433-10-7
2-(methylthio)-4-phenyl-1H-imidazole

Guidance literature:: S-methylisothiourea hemisulphate; With sodium hydrogencarbonate; In tetrahydrofuran; water; at 20 ℃; Reflux;

α-bromoacetophenone; In tetrahydrofuran; water; Reflux;
DOI:10.1021/acs.jmedchem.7b00316

Reference yield:

: 98-86-2
acetophenone

: 25433-10-7
2-(methylthio)-4-phenyl-1H-imidazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: bromine / dichloromethane / 20 °C

2.1: sodium hydrogencarbonate / tetrahydrofuran; water / 20 °C / Reflux

2.2: Reflux

With bromine; sodium hydrogencarbonate; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/acs.jmedchem.7b00316