1-(4-Fluorophenyl)-2-methylpropan-1-one

Base Information

Chemical Name:1-(4-Fluorophenyl)-2-methylpropan-1-one
CAS No.:26393-91-9
Molecular Formula:C10H11FO
Molecular Weight:166.195
Hs Code.:2914700090
European Community (EC) Number:672-528-5
DSSTox Substance ID:DTXSID30382326
Nikkaji Number:J986.979D
Wikidata:Q82173651
Mol file:26393-91-9.mol

Synonyms:1-(4-fluorophenyl)-2-methylpropan-1-one;26393-91-9;4'-fluoroisobutyrophenone;1-Propanone, 1-(4-fluorophenyl)-2-methyl-;MFCD04038305;1-(4-fluoro-phenyl)-2-methyl-propan-1-one;p-Fluoroisobutyrophenone;SCHEMBL204960;Isopropyl p-fluorophenyl ketone;p-Fluorophenyl isopropyl ketone;4'-Fluoro-2-methylpropiophenone;DTXSID30382326;MHUVRVXSYXJUPK-UHFFFAOYSA-N;BBL100424;STL554218;AKOS000346341;AS-10147;1-(4-fluorophenyl)-2-methyl-1-propanone;1-(4Fluoro-phenyl)-2-methyl-propan-1-one;CS-0131584;FT-0676820;1 -(4-Fluoro-phenyl)-2-methyl-propan-1-one;N12099;A818422;1-(4-Fluorophenyl)-2-methyl-1-propanone, AldrichCPR

Suppliers and Price of 1-(4-Fluorophenyl)-2-methylpropan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(4-Fluorophenyl)-2-methylpropan-1-one
500mg
$ 90.00

SynQuest Laboratories
1-(4-Fluorophenyl)-2-methylpropan-1-one
25 g
$ 1136.00

SynQuest Laboratories
1-(4-Fluorophenyl)-2-methylpropan-1-one
5 g
$ 272.00

SynQuest Laboratories
1-(4-Fluorophenyl)-2-methylpropan-1-one
1 g
$ 108.00

Matrix Scientific
1-(4-Fluorophenyl)-2-methylpropan-1-one
1g
$ 49.00

Crysdot
1-(4-Fluorophenyl)-2-methylpropan-1-one 97%
25g
$ 503.00

Chemenu
1-(4-Fluorophenyl)-2-methylpropan-1-one 95+%
25g
$ 475.00

Apolloscientific
4'-Fluoro-2-methylpropiophenone
5g
$ 170.00

Apolloscientific
4'-Fluoro-2-methylpropiophenone
1g
$ 67.00

Apolloscientific
4'-Fluoro-2-methylpropiophenone
25g
$ 710.00

Total 24 raw suppliers

Chemical Property of 1-(4-Fluorophenyl)-2-methylpropan-1-one

Chemical Property:

Refractive Index:1.4980
Boiling Point:95-97/7mm
PSA：17.07000
Density:1.048±0.06 g/cm3(Predicted)
LogP:2.66440
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:166.079393132
Heavy Atom Count:12
Complexity:157

Purity/Quality:

97% ^*data from raw suppliers

1-(4-Fluorophenyl)-2-methylpropan-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(=O)C1=CC=C(C=C1)F

Technology Process of 1-(4-Fluorophenyl)-2-methylpropan-1-one

There total 21 articles about 1-(4-Fluorophenyl)-2-methylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 67-56-1
methanol

: 456-03-1
1-(4-fluorophenyl)propan-1-one

: 26393-91-9
1-(4-fluorophenyl)-2-methylpropan-1-one

Guidance literature:: With C₃₄H₂₇IrN₂P⁽¹⁺⁾*C₃₂H₁₂BF₂₄^(1-); caesium carbonate; at 65 ℃; for 24h; Inert atmosphere;
DOI:10.1002/chem.201405990

Reference yield: 88.0%

: 403-42-9
1-(4-fluorophenyl)ethanone

: 74-88-4
methyl iodide

: 26393-91-9
1-(4-fluorophenyl)-2-methylpropan-1-one

Guidance literature:: With 18-crown-6 ether; potassium hydroxide; In toluene; at 70 ℃; for 24h;
DOI:10.1021/acs.orglett.7b02931

Reference yield: 86.0%

: 1194-02-1,143234-87-1
4-fluorobenzonitrile

: 920-39-8
isopropylmagnesium bromide

: 26393-91-9
1-(4-fluorophenyl)-2-methylpropan-1-one

Guidance literature:: 4-fluorobenzonitrile; isopropylmagnesium bromide; With copper(I) bromide; In tetrahydrofuran; 2-methyltetrahydrofuran; at 0 - 60 ℃; for 4h; Inert atmosphere;

With water; In tetrahydrofuran; 2-methyltetrahydrofuran; at 0 ℃; Inert atmosphere;

With sulfuric acid; In tetrahydrofuran; 2-methyltetrahydrofuran; for 1h; Inert atmosphere; Reflux;
DOI:10.1021/ja300503k