(1E)-N-(3-Methylphenyl)-1-phenylethan-1-imine

Base Information

• Chemical Name: (1E)-N-(3-Methylphenyl)-1-phenylethan-1-imine
• CAS No.: 26625-24-1
• Molecular Formula: C15H15N
• Molecular Weight: 209.291
• DSSTox Substance ID: DTXSID80506151
• Mol file: 26625-24-1.mol

Synonyms:26625-24-1;(1E)-N-(3-Methylphenyl)-1-phenylethan-1-imine;SCHEMBL15137101;SCHEMBL15137103;DTXSID80506151;AKOS015996442

Chemical Property of (1E)-N-(3-Methylphenyl)-1-phenylethan-1-imine

Chemical Property:

• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 209.120449483
• Heavy Atom Count: 16
• Complexity: 238

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)N=C(C)C2=CC=CC=C2

Technology Process of (1E)-N-(3-Methylphenyl)-1-phenylethan-1-imine

There total 6 articles about (1E)-N-(3-Methylphenyl)-1-phenylethan-1-imine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

acetophenone (98-86-2) + 1-amino-3-methylbenzene (108-44-1) → 3-methyl-N-(1-phenylethylidene)aniline (26625-24-1)

Guidance literature:

In diethyl ether; for 24h; Molecular sieve;

DOI:10.1002/adsc.201000733

Reference yield:

phenylacetylene (536-74-3) + 1-amino-3-methylbenzene (108-44-1) → 3-methyl-N-(1-phenylethylidene)aniline (26625-24-1)

Guidance literature:

With C₃₈H₆₆N₄O₂Zr; trityl tetrakis(pentafluorophenyl)borate; In chlorobenzene; at 120 ℃; for 1h; regioselective reaction; Inert atmosphere; Glovebox;

DOI:10.1021/om401158a

Reference yield:

2-phenyl-2-(m-tolylamino)propanenitrile (81512-07-4) → 3-methyl-N-(1-phenylethylidene)aniline (26625-24-1)

Guidance literature:

With potassium hydroxide; In methanol; for 0.75h; Heating;

upstream raw materials:

acetophenone

1-amino-3-methylbenzene

2-phenyl-2-(m-tolylamino)propanenitrile

2-hydroxy-2-phenylpropionitrile

Downstream raw materials:

2,2-Dichloro-3-phenyl-1-m-tolyl-aziridine

N-(2-phenylethyl)-m-toluidine

acetophenone

1-amino-3-methylbenzene