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Sulfosalicylic acid

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Name

Sulfosalicylic acid

EINECS 202-555-6
CAS No. 97-05-2 Density 1.771 g/cm3
PSA 120.28000 LogP 1.41790
Solubility N/A Melting Point 120 °C
Formula C7H6O6S Boiling Point 328.86°C (rough estimate)
Molecular Weight 218.187 Flash Point N/A
Transport Information UN 1760 Appearance White to off-white, hygroscopic, crystalline powder
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 97-05-2 (Benzoic acid,2-hydroxy-5-sulfo-) Hazard Symbols N/A
Synonyms

Salicylicacid, 5-sulfo- (8CI);2-Hydroxy-5-sulfobenzoic acid;3-Carboxy-4-hydroxybenzenesulfonic acid;5-(Hydroxysulfonyl)salicylic acid;5-Sulfosalicylic acid;5-Sulphosalicylic acid;NSC 190565;NSC 4741;SSA;Salicylsulfonic acid;Sulfosalicylic acid;Sulphosalicylic acid;

 

Sulfosalicylic acid Synthetic route

118-55-8

phenyl Salicylate

97-05-2

5-sulfosalicylic Acid

Conditions
ConditionsYield
With sulfuric acid
69-72-7

salicylic acid

97-05-2

5-sulfosalicylic Acid

Conditions
ConditionsYield
With sulfuric acid
With sulfur trioxide
With sulfuric acid
With sulfuric acid Abpressen des entstandenen Krystallbreis und Eintragen in gesaettigte Kochsalzloesung;
With chlorosulfonic acid at 160℃; Zersetzung des Produktes mit Wasser;
27279-86-3

2-oxo-2H-chromene-6-sulfonic acid

alkaline permanganate solution

alkaline permanganate solution

97-05-2

5-sulfosalicylic Acid

69089-38-9

2-oxo-2H-chromene-3,6-disulfonic acid

alkaline permanganate solution

alkaline permanganate solution

97-05-2

5-sulfosalicylic Acid

4-methyl-2-oxo-2H-chromene-6-sulfonic acid

permanganate

permanganate

barytesalkali

barytesalkali

97-05-2

5-sulfosalicylic Acid

4-methyl-2-oxo-2H-chromene-3,6-disulfonic acid

permanganate

permanganate

barytesalkali

barytesalkali

97-05-2

5-sulfosalicylic Acid

118-55-8

phenyl Salicylate

sulfuric acid (excess)

sulfuric acid (excess)

97-05-2

5-sulfosalicylic Acid

7790-94-5

chlorosulfonic acid

69-72-7

salicylic acid

97-05-2

5-sulfosalicylic Acid

Conditions
ConditionsYield
at 160℃;
7664-93-9

sulfuric acid

69-72-7

salicylic acid

97-05-2

5-sulfosalicylic Acid

7446-11-9

sulfur trioxide

69-72-7

salicylic acid

97-05-2

5-sulfosalicylic Acid

Sulfosalicylic acid Chemical Properties

Empirical Formula: C7H6O6S
Molecular Weight: 218.1839 
EINECS: 202-555-6 
Index of Refraction: 1.649
Density: 1.771 g/cm3
Melting point: 120 °C
Appearance: White crystal or crystalline powder
Solubility: Soluble in water and Ethanol, soluble in Ether
Structure of 5-Sulphosalicylic acid (CAS NO.97-05-2):
                  

Sulfosalicylic acid Uses

 5-Sulphosalicylic acid (CAS NO.97-05-2) can be used as a pharmaceutical intermediate, and has been used in medicine doxycycline and A production of rare earth mycin.

Sulfosalicylic acid Production

 5-Sulphosalicylic acid (CAS NO.97-05-2) can be derived from salicylic acid obtained by sulfonation.

Sulfosalicylic acid Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rabbit LDLo oral 1300mg/kg (1300mg/kg)   "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 565, 1969.
rabbit LDLo skin 7940mg/kg (7940mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: FOOD INTAKE (ANIMAL)
National Technical Information Service. Vol. OTS0570587,
rat LD50 oral 1850mg/kg (1850mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: FOOD INTAKE (ANIMAL)
GASTROINTESTINAL: OTHER CHANGES
National Technical Information Service. Vol. OTS0570587,

Sulfosalicylic acid Consensus Reports

Reported in EPA TSCA Inventory.

Sulfosalicylic acid Safety Profile

Moderately toxic by ingestion. Irritating to skin and mucous membranes. When heated to decomposition it emits toxic fumes of SOx. See also SULFONATES.

Sulfosalicylic acid Specification

 5-Sulphosalicylic acid ,its cas register number is 97-05-2. It also can be called 2-Hydroxy-5-sulfo-benzoic acid ; Benzoic acid, 2-hydroxy-5-sulfo- and Sulfosalicylic acid . 2 - hydroxy -5 - methyl-benzoic acid dihydrate is a white crystal or crystalline powder.

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