Hot Products

Basic Information

Post buying leads

Suppliers

Cas Database

Name	Tetrabutylurea	EINECS	224-929-8
CAS No.	4559-86-8	Density	0.886 g/cm³
PSA	23.55000	LogP	4.91080
Solubility	4.3mg/L at 20℃	Melting Point	<-50oC
Formula	C₁₇H₃₆N₂O	Boiling Point	379.8 °C at 760 mmHg
Molecular Weight	284.486	Flash Point	132 °C
Transport Information	N/A	Appearance	N/A
Safety	22-24/25	Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	Urea,1,1,3,3-tetrabutyl- (6CI,7CI);Urea, tetrabutyl- (8CI,9CI);1,1,3,3-Tetrabutylurea;NSC 3892;	Article Data	22

Tetrabutylurea Synthetic route

: 160594-75-2
Tetrabutyl-selenourea

: 4559-86-8
N,N,N',N'-Tetrabutylurea

Conditions

Conditions	Yield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0℃; for 3h;	100%

: 32315-10-9
bis(trichloromethyl) carbonate

: 111-92-2
dibutylamine

: 4559-86-8
N,N,N',N'-Tetrabutylurea

Conditions

Conditions	Yield
In water at 0 - 5℃; for 2h; Temperature;	92.4%

: 111-92-2
dibutylamine

: 616-38-6
carbonic acid dimethyl ester

: 4559-86-8
N,N,N',N'-Tetrabutylurea

Conditions

Conditions	Yield
With sodium methylate In methanol at 30 - 60℃; for 5h; Temperature; Solvent; Reagent/catalyst; Reflux;	90.9%

: 75-44-5
phosgene

: 111-92-2
dibutylamine

: 4559-86-8
N,N,N',N'-Tetrabutylurea

Conditions

Conditions	Yield
With sodium hydroxide In H20 at 75 - 85℃; for 5.75 - 7h; pH=10 - 11; Product distribution / selectivity;	88%
With potassium carbonate
With potassium carbonate In benzene

: 124-38-9
carbon dioxide

: 111-92-2
dibutylamine

: 4559-86-8
N,N,N',N'-Tetrabutylurea

Conditions

Conditions	Yield
Stage #1: carbon dioxide; dibutylamine In dimethyl sulfoxide at 20℃; Stage #2: dibutylamine With triphenylphosphine; diethylazodicarboxylate In dimethyl sulfoxide at 20℃; for 3h; chemoselective reaction;	84%
With potassium hydroxide at 149.84℃; under 60006 Torr; for 10h; Autoclave;	36.7%
Stage #1: carbon dioxide; dibutylamine With 1,8-dimethylaminonaphthalene In tetrahydrofuran at 20℃; under 750.075 Torr; for 1h; Stage #2: dibutylamine In tetrahydrofuran; tetrachloromethane at 60℃; for 23h; Further stages.;	99 % Spectr.

: O-trifluoromethanesulfonyl-N,N,N',N'-tetrabutyluronium triflate

: 109-89-7
diethylamine

A: 357-39-1
N,N-diethyl-1,1,1-trifluoromethanesulfonamide

B: 4559-86-8
N,N,N',N'-Tetrabutylurea

C: 60933-18-8
diethylammonium trifluoromethanesulfonate

Conditions

Conditions	Yield
In chloroform at 4℃; for 72h;	A 55% B 74% C n/a

: 201230-82-2
carbon monoxide

: 111-92-2
dibutylamine

A: 4559-86-8
N,N,N',N'-Tetrabutylurea

B: 132279-00-6
N,N,N',N'-Tetrabutyl-2-oxo-malonamide

C: 83862-73-1
N,N-dibutylglyoxylamide hemihydrate

Conditions

Conditions	Yield
Yield given. Multistep reaction. Yields of byproduct given;

: 102-01-2
N-phenylacetoacetamide

: 111-92-2
dibutylamine

A: 4559-86-8
N,N,N',N'-Tetrabutylurea

B: 2589-21-1
1,1'-dibutyl-3-phenylurea

Conditions

Conditions	Yield
With zeolite HSZ-360 at 180℃; for 3h; Condensation;

: O-trifluoromethanesulfonyl-N,N,N',N'-tetrabutyluronium triflate

: 108-18-9
diisopropylamine

A: C7H14F3NO2S

B: 4559-86-8
N,N,N',N'-Tetrabutylurea

C: 77534-66-8
diisopropylammonium trifluoromethanesulfonate

Conditions

Conditions	Yield
In chloroform at 4℃; for 72h;

: O-trifluoromethanesulfonyl-N,N,N',N'-tetrabutyluronium triflate

: 111-92-2
dibutylamine

A: C9H18F3NO2S

B: dibutylammonium trifluoromethanesulfonate

C: 4559-86-8
N,N,N',N'-Tetrabutylurea

Conditions

Conditions	Yield
In chloroform at 4℃; for 72h;

Tetrabutylurea Specification

The Tetrabutylurea, with the CAS registry number 4559-86-8, is also known as Urea, 1,1,3,3-tetrabutyl-. It belongs to the product category of Phosgene Derivatives. Its EINECS registry number is 224-929-8. This chemical's molecular formula is C₁₇H₃₆N₂O and molecular weight is 284.48054. Its IUPAC name is called Tetrabutylurea. This chemical's classification code is Reproductive Effect. When you are using this chemical, please be cautious about it. You should not breathe its dust. What's more, you must avoid contact with skin and eyes. Tetrabutylurea is mainly used as solvents in production of hydrogen peroxide via AQ reaction. It also can be used as the products instead of trioctyl phosphate.

Physical properties of Tetrabutylurea: (1)ACD/LogP: 6.57; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): 6.57; (4)ACD/LogD (pH 7.4): 6.57; (5)ACD/BCF (pH 5.5): 57585.23; (6)ACD/BCF (pH 7.4): 57585.3; (7)ACD/KOC (pH 5.5): 88922.63; (8)ACD/KOC (pH 7.4): 88922.73; (9)#H bond acceptors: 3; (10)#Freely Rotating Bonds: 12; (11)Index of Refraction: 1.462; (12)Molar Refractivity: 88.27 cm³; (13)Molar Volume: 320.7 cm³; (14)Surface Tension: 32.3 dyne/cm; (15)Density: 0.886 g/cm³; (16)Flash Point: 132 °C; (17)Enthalpy of Vaporization: 62.79 kJ/mol; (18)Boiling Point: 379.8 °C at 760 mmHg; (19)Vapour Pressure: 5.7E-06 mmHg at 25°C.

Preparation of Tetrabutylurea: this chemical can be prepared by carbonochloridic acid ethyl ester and Dibutyl-lithiumamid. This reaction will need solvent tetrahydrofuran. The reaction time is 1 day at ambient temperature. The yield is about 30%.

Tetrabutylurea can be prepared by carbonochloridic acid ethyl ester and Dibutyl-lithiumamid

Uses of Tetrabutylurea: it can be used to produce N,N,N'N'-Tetrabutylchloroamidinium chloride at temperature of 80 °C. This reaction will need reagent COCl₂ with reaction time of 2 hours. The yield is about 83%.

Tetrabutylurea can be used to produce N,N,N'N'-Tetrabutylchloroamidinium chloride

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: CCCCN(CCCC)C(=O)N(CCCC)CCCC
(2)InChI: InChI=1S/C17H36N2O/c1-5-9-13-18(14-10-6-2)17(20)19(15-11-7-3)16-12-8-4/h5-16H2,1-4H3
(3)InChIKey: SNDGLCYYBKJSOT-UHFFFAOYSA-N

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rat	LCLo	inhalation	700mg/m³/4H (700mg/m³)		Food and Chemical Toxicology. Vol. 25, Pg. 173, 1987.
rat	LD50	oral	17gm/kg (17000mg/kg)		Food and Chemical Toxicology. Vol. 25, Pg. 173, 1987.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 4559-86-8