This is an enzyme involved in the cleavage of certain proteins, including the amyloid precursor protein (APP). Abnormal cleavage of APP can lead to the formation of amyloid beta (Aβ) plaques in the brain, a hallmark of Alzheimer's disease. γ-Secretase inhibitors are potential drugs aimed at modulating this process and reducing Aβ plaque formation, with the hope of slowing down or preventing the progression of Alzheimer's disease.
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C17H21N3O2
C20H19ClF2O5S
C19H14F6O4S
C16H15ClF3NO3S
(R)-N-(4-fluorophenyl)-3-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-4,5,6,7-tetrahydrobenzo[d]isoxazol-7-amine
