Benchmarking

Evaluating the performance of a catalyst or reaction by comparing it to established standards or benchmarks

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Aluminum-Mediated Formation of Cyclic Carbonates: Benchmarking Catalytic Performance Metrics
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- (+/-)-trans-4,5-dimethyl-1,3-dioxolan-2-one
Double asymmetric iodoamination; synthesis of C₂ symmetric and meso-amino alcohols
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- ((1S,2R,3S,4R)-1-Benzyl-4-tert-butoxycarbonylamino-2,3-dihydroxy-5-phenyl-pentyl)-carbamic acid tert-butyl ester

Regioselectivity Diastereoselectivity Green chemistry Solid-phase synthesis Microwave-assisted synthesis Yield NMR spectroscopy Enantioselectivity Enantiomeric excess (ee) Chromatography Recrystallization Stereoselective synthesis Mass spectrometry (MS) Nucleophilic substitution Atom economy one-pot synthesis Cross-coupling Electrochemistry Hydrogen bonding TLC (thin-layer chromatography) Protecting group Epimerization Resolution X-ray crystallography Leaving group Chelation Catalytic asymmetric synthesis Purification Metathesis Ligand Design Retrosynthetic analysis Workup Reductive Elimination Organocatalysis Biocatalysis Substrate Scope Collaboration Solvent Effects Structure-Activity Relationship (SAR) Catalyst Loading Reaction Monitoring Computational Chemistry Waste Disposal Ethical Considerations Chiral Auxiliary High-Throughput Screening (HTS) Temperature Control Chiral Pool Synthesis Dynamic Kinetic Resolution Protecting group strategy

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