Double asymmetric iodoamination; synthesis of C2 symmetric and meso-amino alcohols

DOI: 10.1039/cc9960000355

Source and publish data:

Chemical Communications p. 355 - 356 (1996)

Update date:2022-08-02

Topics: Regioselectivity Diastereoselectivity Green chemistry Solid-phase synthesis Microwave-assisted synthesis Yield NMR spectroscopy Enantioselectivity Enantiomeric excess (ee) Chromatography Recrystallization Stereoselective synthesis Mass spectrometry (MS) Nucleophilic substitution Atom economy one-pot synthesis Cross-coupling Electrochemistry Hydrogen bonding TLC (thin-layer chromatography) Protecting group Epimerization Resolution X-ray crystallography Leaving group Chelation Catalytic asymmetric synthesis Purification Metathesis Ligand Design Retrosynthetic analysis Workup Reductive Elimination Organocatalysis Biocatalysis Substrate Scope Collaboration Solvent Effects Structure-Activity Relationship (SAR) Catalyst Loading Reaction Monitoring Computational Chemistry Waste Disposal Ethical Considerations Chiral Auxiliary High-Throughput Screening (HTS) Temperature Control Chiral Pool Synthesis Dynamic Kinetic Resolution Protecting group strategy

Authors:

Kang, Sung Ho

Ryu, Do Hyun

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/cc9960000355

Alkenic diols 2 and 14 are iodocyclized providing dihydro-1,3-oxazine 3 and dihydrooxazole 15 in 90 and 93% de, respectively, which are precursors of various C₂ symmetric and meso-amino alcohols.

Full text of DOI:10.1039/cc9960000355

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:O²,O³-isopropylidene-D-threose

Cas No:51607-17-1

R&D Labs maybe for 51607-17-1

Anqing World Chemical Co., Ltd.

Contact:+86-556-5800026

Address:Daguan Economic Development Zone of circular economy industrial park Anqing City Anhui province
STAR SYNTHESIS CO.,LIMITED

Contact:+(852) 301-98033

Address:Flat C, 23/F, Lucky Plaza, 315-321 Lockhart Road, Wan Chai, Hong Kong
Tai zhou world Pharm & Chem Co., Ltd

Contact:+86-576-85301198

Address:Rome 1001,wangjiang plaza,unti 2,jinshan east Road linhai,zhejiang,china
Xi'an yuanfar international trade company

website:https://www.yuanfarchemical.com

Contact:86-029-88745613 ext 828

Address:Floor19th ,B Building, Oak Block,No.36 South Fenghui Road, Dev. Zone of High-Tech Ind.,Xi’an, China
KINHENG CHEMICAL(SHANGHAI)CO., LTD.

Contact:+8621-60490170

Address:Room401, No.28,Lane 189, Yangshupu Rd. Shanghai, China.

Relevant to this article

REACTIONS OF 2,4,6-TRIARYL-DIHYDRO-1,3,5-DITHIAZINES WITH ELECTROPHILIC REAGENTS

Doi:10.1246/cl.1983.1503
(1983)
Synthesis and stereochemistry-activity relationship of small bacteriocin, an autoinducer of the symbiotic nitrogen-fixing bacterium rhizobium Leguminosarum

Doi:10.1021/ol8005198
(2008)
Packing and compositional disorder with MoO₂Cl₂(OPMePh₂)₂, MoOCl₃(OPMePh₂)₂ and MoCl₄(OPMePh₂)₂ as assessed by single crystal X-ray diffraction

Doi:10.1016/S0020-1693(02)01157-X
(2003)
Lithiophenylalkyllithiums: New dilithium reagents having both sp²- and sp³-hybridised remote carbanionic centres

Doi:10.1016/S0022-328X(02)01473-0
(2002)
Cycloaldol approach to the isobenzofuran core of eunicellin diterpenes

Doi:10.1021/ol034052f
(2003)
Amine- and ether-chelated aryllithium reagents - Structure and dynamics

Doi:10.1021/ja028301r
(2003)

Article Doi