Bicyclic System

Synthesis Yield NMR spectroscopy Reactivity Nucleophile Derivatives Kinetic studies Steric hindrance Leaving group Purification Reaction Conditions Nucleophilic Attack Electronic effects Substitution Reaction Substrate Scope Computational Modeling Reaction Monitoring Base-Catalyzed Hydrolysis Copper-Catalyzed Ring Fusion Aryl Amines Spectroscopic Analysis Ring Strain Heterocyclic compound Electrophilic Ortho Sulfonyl group Imidazole Amide bond Oxazole pH dependence Hydrolysis resistance Control experiment Isolation of intermediates