Use relevant immune cells or cell lines (e.g., macrophages) to evaluate the immunomodulatory effects of your derivatives. Measure cytokine production, NF-κB activation, and other immune response parameters in the presence of LPS and your modified lipid A derivatives.
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Allyl 3-O-<(3R)-3-benzyloxytetradecanyl>-2-deoxy-4,6-O-isopropylidene-2-trifluoroacetamido-α-D-glucopyranoside
trichloroacetonitrile
calysolic acid A
Boc-L-isoleucine methyl ester
2-<2-(4-Hydroxy-3-methoxyphenyl)ethyl>-1,3-dithiane
