Investigate the SAR to optimize the structural features of your ether-modified lipid A derivatives that lead to the most effective LPS antagonistic activity.
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Allyl 3-O-<(3R)-3-benzyloxytetradecanyl>-2-deoxy-4,6-O-isopropylidene-2-trifluoroacetamido-α-D-glucopyranoside
trichloroacetonitrile
1-(4-amino-3-n-butoxyphenyl)ethanone
4-fluoro-2-(methoxycarbonylmethyl)benzenesulfonamide
2-benzyloxycarbonylamino-3-iodo-propionic acid tert-butyl ester
1H-INDOLE,3-(2-CHLOROETHYL)-5-METHOXY-
Indole
5-Methoxyindole
3-(anilinocarbonyl)-2-pyrazinecarboxylic acid
2'-((4-nitrophenyl)carbamoyl)-[1,1'-biphenyl]-2-carboxylic acid
3-(4-methoxyphenyl)-1-pyridin-3-ylprop-2-en-1-one
3-[2-(6-chloropyridazin-3-ylamino)phenylamino]-1H-pyrazol-5(4H)-one
C15H10BrClO2
1-[5-(2-Fluoropyridin-3-yl)-1-(phenylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate
(R)-2-(4-amino-4-carboxybut-1-en-1-yl)benzoic acid
1-phenylacetyl-4-[2-(tert-butoxycarbonylamino)acetyl]piperazine
N-(4-phenoxyphenyl)-2-furamide
3-carbamoyl-1-[2-(4-fluorophenyl)-2-oxoethyl]pyridinium
dehydroandrographolide
methyl 3-(4-((2-chloropyridin-4-yl)ethynyl)phenyl)propanoate
Boc-D-Lys(Cl-Z)-D-Leu-Pro-OMe
3-Heptanone, 1,7-bis(4-hydroxy-3-methoxyphenyl)-
Carbamic acid, [2-oxo-2-[(2-phenylethyl)amino]ethyl]-, phenylmethyl ester
tert-butyl (S)-3-((5-bromo-2-chloropyrimidin-4-yl)amino)piperidine-1-carboxylate
bis(benzonitrile)palladium(II) dichloride
C17H20N2O
(3S,6S,7R)-3-benzyloxymethyl-7-tertbutyldiphenylsilyloxymethyl-4-N-methyl-6-palmitoyloxy-1,4-diazepan-2-one
E-3-(5-benzylidene-2-oxo-5,6-dihydro-2H-pyran-3-yl)propionic acid methyl ester
anisaldehyde
Triethylamine
C20H14BrN3O5
1H-Isoindole-1,3(2H)-dione, 2-[2-[(3-hydroxypropyl)(phenylmethyl)amino]ethyl]-
(E)-methyl 3-(4-chlorophenyl)-2-((octylamino)methyl)acrylate
{(S)-3-Benzyloxy-1-[(2S,6R)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-tetrahydro-pyran-2-ylmethyl]-propoxy}-tert-butyl-diphenyl-silane
1-Piperazinecarbodithioicacid,methylester(9CI)
N-(4-chloro-3-fluorophenyl)-2-(5-methoxy-1H-benzo[d]imidazol-2-ylthio)acetamide
C16H18N4O2
2-amino-4-ethoxy-5-methoxybenzonitrile
4-(bromomethyl)-N-cyclohexyl-N-methylbenzenesulfonamide
12
2,3-dibromo-1-(bromomethyl)-4,5-dimethoxybenzene
2-amino-4-(4-fluorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile
4-BroMo-5,7-diMethyl-2,3-dihydro-1H-inden-1-one
2-CYANO-N-CYCLOPROPYL-ACETAMIDE
Glycine, N-[(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-, (2S)-
methyl 1-(4-chlorobenzyl)-1H-pyrrole-2-carboxylate
N-((1S,2R,3S,4R)-4-[2-chloro-6-(2,2-diphenyl-ethylamino)-purin-9-yl]-2,3-dihydroxy-cyclopentyl)-2,2-dimethyl-propionamide
tert-butyl 4-(4-cyanobenzylcarbamoyl)piperidine-1-carboxylate
3-{[(1S)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione
(4-(2-hydroxyethoxy)phenyl)(6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl)methanone
7-(phenethoxy)-1-methyl-β-carboline
ethyl (8R,9S)-8-[[(1R)-1-phenylethyl]amino]-1,4-dioxaspiro[4.5]decane-9-carboxylate
N-(4-bromo-benzyl)-ethylenediamine
(((15-bromopentadecyl)oxy)methyl)benzene
1,7-bis(4-hydroxy-3-methoxyphenyl)-4-(2-(p-tolyl)hydrazono)hepta-1,6-diene-3,5-dione
