Boc (tert-Butyloxycarbonyl)

A common amine-protecting group in peptide synthesis.

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Studies on peptides. CXXVI. Synthesis of the protected tetracosapeptide corresponding to positions 30-53 of mouse epidermal growth factor (EGF)
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Synthesis Peptide Solid-phase synthesis Yield Cleavage Mass spectrometry (MS) High-performance liquid chromatography (HPLC) Deprotection HPLC (high-performance liquid chromatography) NMR (nuclear magnetic resonance) Protecting group Nuclear Magnetic Resonance (NMR) Purification Scale-up Solid-Phase Peptide Synthesis (SPPS) Coupling Reaction Amino Acid Sequence Purity Peptide bond Resin Enkephalin Solid phase synthesis Cyclic peptide Protected peptide Activating reagents Fmoc (Fluorenylmethyloxycarbonyl) TFA (Trifluoroacetic Acid) Lyophilization (Freeze-Drying) DCC (Dicyclohexylcarbodiimide) HOBt (Hydroxybenzotriazole) CD (Circular Dichroism) Resin (Solid Support) Cleavage (from resin) Triphenylphosphine (PPh?)

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