HOBt (Hydroxybenzotriazole)

An additive to improve coupling efficiency.

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Synthesis Peptide Solid-phase synthesis Yield Cleavage Mass spectrometry (MS) Solubility Deprotection HPLC (high-performance liquid chromatography) NMR (nuclear magnetic resonance) Protecting group Purification Peptide Synthesis Circular Dichroism (CD) Coupling Solid-Phase Peptide Synthesis (SPPS) Coupling Reaction Biological Activity Activation Receptor Binding Amino Acid Sequence Purity Peptide bond Resin Protected peptide Linker Aggregation Retention time Fmoc (Fluorenylmethyloxycarbonyl) TFA (Trifluoroacetic Acid) Lyophilization (Freeze-Drying) Boc (tert-Butyloxycarbonyl) DCC (Dicyclohexylcarbodiimide) CD (Circular Dichroism) Fmoc chemistry Resin (Solid Support) DIC (Diisopropylcarbodiimide) Secondary Structure Side-chain protection

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