The 3,4-dihydroisoquinolin-1(2H)-one derivatives are synthesized as potential radiotracers. This involves designing and optimizing the chemical structure of the radioligands to ensure high affinity and selectivity for σ2 receptors.
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2-(3-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)propyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-1(2H)-one
