a. Select the most promising compounds for in vivo testing in animal models (e.g., rodents, dogs, or non-human primates). b. Assess the compounds' ability to block AVP-induced vasoconstriction, while also evaluating their pharmacokinetics and toxicity.
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3-MERCAPTO-3-METHYL-BUTYRYL-TYR-PHE-VAL-ASN-CYS-PRO-D-ARG-GLY-NH2
3-bromo-4'-amino-chalcone
N-(3-chlorobenzyl)-N-methylpiperidin-4-amine
2-(3-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)propyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-1(2H)-one
6-[(4-Chloro-phenyl)-hydrazono]-6,7,8,9-tetrahydro-11H-pyrido[2,1-b]quinazoline-11-one
Methyl 5-Methoxy-2-nitro-4-(3-(pyrrolidin-1-yl)propoxy)benzoate
5-BROMO-2-[(4-CHLOROBENZYL)OXY]BENZALDEHYDE
4-isopropylbenzenesulfonyl azide
N-(3,4-dichlorophenyl)-N'-(1-methyl-4-oxo-4,5-dihydro-1H-imidazol-2-yl)guanidine
N-(3-((diethylamino)methyl)-2-ethoxybenzylidene)isonicotinohydrazide
7-{2-[1-(4-(2-fluorophenyl)piperazin-1-yl)-2-oxopropylidene]hydrazinyl}-4-methyl-2H-chromen-2-one
3-cyclohexyl-2-imino-5,5-diphenylimidazolidin-4-one
4-methylphenyl 3-[({7-[({7-[({3-[(4-methylphenyl)oxysulfonyl]phenyl}amino)sulfonyl]-2-naphthyl}amino)carbonylamino]-2-naphthyl}sulfonyl)amino]benzenesulfonate
5-Amino-2-chlorobenzoic acid
Pyridine
5-[4-(3-ethyl-3H-imidazo[4,5-b]pyridin-2-ylmethoxy)benzyl]-3-triphenylmethylthiazolidine-2,4-dione
Acetic acid, hydroxy-, (4-methoxyphenyl)methyl ester
ETHYL (S)-(-)-2-((METHYLSULFONYL)OXY)-PROPIONATE, TECH., 90
ETHYL MANDELATE
7-methoxy-8-{6-[2-methoxy-4-[(E)-3-morpholino-3-oxo-1-propenyl]phenoxy]hexyloxy}-(11aS)-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one
2,6-Piperidinedione, 3-(4-aminophenyl)-3-methyl-
methyl acetamido-2,6-anhydro-3,5-dideoxy-9-p-toluenesulfonyl-D-glycero-D-galactonon-2-enonate
1-(3-Methoxymethyl-4-oxiranylmethoxy-phenyl)-ethanone
Fumaric acid
2-(4-{[(3-fluorophenyl)amino]carbonothioyl}-1-piperazinyl)-8-ethyl-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid
(R)-(+)-2-(α-(i-butyl)MethanaMine)-1H-benziMidazole, Min. 98% (R)-i-Bu-BIMAH
ACETIC ACID
N-(4-((4'-(benzyloxy)phenyl)(hydroxy)-methyl)phenyl)propionamide
N1-(7-chloroquinolin-4-yl)-N2-{2-[(dimethylamino)methyl]benzyl}ethan-1,2-diamine
C26H23FO6
2-methylsulfanyl-3-(4-chlorophenyl)-3H-quinazolin-4-one
C25H27N3O9S
2-CHLORO-N-PYRAZIN-2-YLACETAMIDE
2-methyl-5-benzylsulfonylamino-6-oxo-1 6-dihydro-1-pyrimidinylacetic acid
7,8-Methylenedioxy-3-methyl-1-phenyl-3,5-dihydro-2,3-benzodiazepin-4(4H)-one
2-Propenoyl chloride, 3-[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]-, (E)-
[4-(4-methoxyphenyl)piperazin-1-yl](pyridin-3-yl)methanone
6-[(2-phenylhydrazinyl)methylidene]cyclohexa-2,4-dien-1-one
N-methyl-3-phenyl-3-(6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-yloxy)propan-1-amine
2-(diphenylphosphonooxy)ethyl 2-deoxy-6-O-<2-deoxy-4-O-diphenylphosphono-3-O-<(R)-3-tetradecanoyloxytetradecanoyl>-6-O-(2,2,2-trichloroethoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-3-O-tetradecanoyl-2-tetradecanoylamino...
2-(4-Aminophenyl)-2-methylpropanenitrile
8-benzyl-4-methyl-1-oxa-3,8-diaza-spiro[4.5]decan-2-one
(3R)-4-(3-isopropoxyphenyl)-1,3,4-triMethylpiperidine
1-benzyl-4-methyl-3-[4-(methylsulfanyl)phenyl]-4,5-dihydro-1H-pyrazole
2-nitro-5-thiomorpholinophenol
7,10-bis-O-(2,2,2-trichloroethoxycarbonyl)-13-O-{3-(tert-butoxycarbonylamino)-3-[(1-tert-butoxycarbonyl)pyrrole-2-yl]-2,2-difluoropropionyl}-10-deacetylbaccatin III
1H-Pyrazole-4-carboxylic acid, 3-[[(phenylamino)thioxomethyl]amino]-, ethyl ester
