Irreversible inhibitors form a stable covalent bond with the target enzyme, leading to a long-lasting inhibition. In the case of vigabatrin analogs, an irreversible inhibitor would permanently bind to the GABA-AT enzyme, inhibiting its activity for an extended period.
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2-Amino-N-(4-fluorophenyl)acetamide hydrochloride
(R)-2-Benzyl-3-((S)-2-benzyloxycarbonylamino-3,3-dimethyl-butyryl)-succinic acid 4-tert-butyl ester 1-methyl ester
N6-<4-<<<4-<<<<2-<(Bromoacetyl)amino>ethyl>amino>carbonyl>methyl>anilino>carbonyl>methyl>phenyl>adenosine
6-amino-7-methoxyquinazolin-4(3H)-one
2-Butyn-1-one, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-phenyl-
