Modifications can enhance the metabolic stability of these compounds, leading to longer half-lives and improved pharmacokinetics.
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1,3-Dimethyl-8-piperidin-1-yl-7-{2-[piperidin-(2Z)-ylideneamino]-ethyl}-3,7-dihydro-purine-2,6-dione
tert-Butyl 3-{4-[4-(4-amidinophenyl)-1-piperazinyl]phenyl}propionate
Chlorobenzene
4-Methyl-3-(4-Morpholinosulfonyl)aniline
1H-Pyrazole-3-carboxylic acid, 1-[4-(aminosulfonyl)phenyl]-5-(4-methylphenyl)-, ethyl ester
trecetilide
bis[3-(benzenesulfonylamino)propyl]carbamic acid tert-butyl ester
[4-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-cyclohexyl]-carbamic acid tert-butyl ester
(R)-2-Benzyl-3-((S)-2-benzyloxycarbonylamino-3,3-dimethyl-butyryl)-succinic acid 4-tert-butyl ester 1-methyl ester
(R)-4-((2R,3S)-3-((benzyloxy)methyl)oxiran-2-yl)-2,2-dimethyl-1,3-dioxolane
6-(2-(di-n-propylamino)ethyl)indole
4-(3-bromo-2-{2-[(2R)-2-methylpyrrolidin-1-yl]ethyl}-1-benzofuran-5-yl)benzonitrile
methyl 3,5-bis[(acetylsulfanyl)methyl]benzoate
C16H13N5O2
2-methylsulfanyl-3-(4-chlorophenyl)-3H-quinazolin-4-one
7,8-Methylenedioxy-3-methyl-1-phenyl-3,5-dihydro-2,3-benzodiazepin-4(4H)-one
1,3-dihydro-3,3-dimethyl-1-phenylisobenzofuran-1-ol
1-(4-BROMO-PHENYL)-4-METHYL-PIPERAZINE
PF-04457845
1-(3-bromoprop-1-yn-1-yl)-3-fluorobenzene
C17H13N3O3S
1-(4-methoxyphenyl)-7-phenoxyheptane
(S)-[2-(methoxymethoxy)-2-phenyl]ethyl benzoate
1,3-dichloro-2-{2-[4-(iodomethyl)phenoxy]ethoxy}-5-methylbenzene
(E)-N-(3-fluoro-4-(methylsulfonamido)benzyl)-3-(4-iodophenyl)acrylamide
(SS,E)-N-(3-(3,4-dichlorophenyl)propylidene)-2-methylpropane-2-sulfinamide
methyl 3-acetamido-5-(3-methoxyphenyl)pentanoate