It's often necessary to separate the (E,E,E)-chlorotrienes from other isomers (such as (Z,Z,Z)-chlorotrienes or mixtures) to achieve the desired stereocontrolled synthesis. Techniques like column chromatography or crystallization may be employed.
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(3E,5E)-6-chloro-1-(p-methoxyphenyl)hexa-3,5-diene
2-Phenyl-cyclopropanecarboxylic acid 1-isopropyl-1,2-dimethyl-propyl ester
