Substrate Design

Diastereoselectivity Characterization Catalysts Steric hindrance Optimization Cyclopropanation Stereocontrol Computational methods Purification and characterization Workup and Product Isolation Reaction Conditions Work-up and Isolation Steric and Electronic Effects Organocatalysis Work-up and purification Diels-Alder Reaction Chiral Catalysts Tandem Reactions Chiral Catalyst Solvent Effects Temperature and Solvent Substituent Effects Reaction Time Preorganization Analysis Catalyst Selection Catalyst Loading Mechanistic Understanding Chiral Starting Materials Optimization of Reaction Conditions Ligand Screening Analytical Techniques Literature Search Process Optimization Further Functionalization Chiral Bases Bifunctional Catalysts Temperature Control In Situ Activation Reductive Conditions Transition Metal Catalysis Chiral Auxiliaries Ligand Effects Oxidative Conditions Temperature and solvent effects Isomer Separation Reaction Optimization Fischer Indole Synthesis Analytical Methods Scale-Up Considerations