Low-temperature reaction

Synthesis Oxidation 1,2-addition Regioselectivity Column chromatography Yield NMR spectroscopy Nucleophile Electrophile Stereochemistry Deprotonation Carbonyl group Chromatography Recrystallization Nucleophilic substitution Nucleophilic addition Cyclization Kinetics Mechanism Alkene Anhydrous conditions Sulfone Purification Workup Reaction Conditions Intramolecular Reaction Nucleophilic Attack Reaction Mechanism Quenching Lithiation Spectroscopic Characterization Thermogravimetric Analysis (TGA) Spectroscopic Analysis Stoichiometry Stoichiometric Control X-ray Diffraction (XRD) α,β-Unsaturated Ketones Byproduct Aromatic substitution Ring-closing reaction Gas chromatography (GC) Anionic Cyclization Michael acceptor carbanion Organolithium reagent Reaction intermediate Exothermic reaction 1,4-Addition (Conjugate Addition) ACTIVATION ENERGY (E?) TLC monitoring