1,3,5-TRISUBSTITUTED BENZENES I. SYNTHESIS AND REACTIONS OF 3,5-DIBROMOPHENYLLITHIUM

Article abstract of DOI:10.1016/S0022-328X(00)92605-6

An improved method for the synthesis of 3,5-dibromophenyllithium (I) has been developed.The reactions between I and various substrates leads to a variety of substituted compounds e.g. (3,5-Br2C6H3)nX; when n = 1, X = -CO2H, -CHO, -Si(CH3)2Cl, -C(O)C3F7, -C(O)CF2(OCF2CF2)3OC2F5, -C(O)CF(CF3)OC3F7, -C(O)CF(CF3)2OC3F7, -C(CF3)2OH and C6F5; when n = 2, X = p-C6F4; when n = 3, X = P.The thermal stability of I is also reported.