On the flip side, the broad inhibition of the phosphodiesterase family is a potential drawback. Phosphodiesterases play a crucial role in regulating intracellular signaling and have diverse functions. Broad inhibition of this family can lead to off-target effects and potential side effects. It underscores the importance of fine-tuning compound selectivity to avoid unintended consequences.
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6-((6-(3,4-difluorophenyl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl)-methyl)quinoline
2H-Cyclopenta[b]furan-2-carbonitrile,5-(acetyloxy)hexahydro-(9CI)
