Secondary KIE

A KIE from isotopic substitution at adjacent atoms.

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IR spectroscopy Elemental analysis Asymmetric synthesis Regioselectivity Flash chromatography Electron transfer Lewis acid Crystallization Yield NMR spectroscopy Distillation Catalyst Enantioselective Mass spectrometry Ligand Hydrogenation Nucleophile Electrophile Heck reaction Steric hindrance Enantiomeric excess (ee) Carbene Recrystallization Mass spectrometry (MS) Cross-coupling Cyclopropanation Retro-aldol reaction Deprotection Filtration GC (gas chromatography) Precursor Radical reaction Hydrogen bonding pH Microwave irradiation TLC (thin-layer chromatography) HPLC (high-performance liquid chromatography) coordination complex Epoxidation Intramolecular X-ray crystallography Michael addition Leaving group Tautomerism Dielectric constant Chelation Diastereomers Inhibitor Metathesis Isomerization

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