Proton-Transfer Reactions. 4. Near-Unity Kinetic Isotope Effects for Hydron Exchange and Dehydrofluorination Reactions

DOI: 10.1021/ja00346a048

Source and publish data:

Journal of the American Chemical Society p. 2394 - 2398 (1983)

Update date:2022-08-05

Topics: IR spectroscopy Regioselectivity Electron transfer Lewis acid NMR spectroscopy Catalyst Mass spectrometry Nucleophile Electrophile Retro-aldol reaction Hydrogen bonding pH Michael addition Leaving group Tautomerism Buffer Solution Reaction Mechanism UV-Vis Spectroscopy Enolization Substitution Reaction Hydride Transfer Elimination Reaction Solvent Effects Substituent Effects Stereoselectivity Aldol Reaction Substrate Quenching Bond Cleavage Deuterium Labeling Activation Energy Thermodynamic Stability Acid-Base Catalysis Kinetic Control Thermodynamic Control Isotopic Labeling Activation Parameters Flash Photolysis Proton-Coupled Electron Transfer (PCET) Radical mechanism Potential Energy Surface (PES) Bronsted Acid Ionic Strength Kinetic Analysis Reaction rate Standard State Inhibition Lewis base Steric Effect Transition state

Authors:

Koch, Heinz F.

Dahlberg, Donald B.

Lodder, Gerrit

Root, Karen S.

Touchette, Nancy A.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/ja00346a048

Rates and isotope effects are reported for benzylic hydron exchange and dehydrofluorination reactions of C6H5CⁱHClCF3 (I) and C6H5CⁱH(CF3)2 (II) in alcoholic sodium alkoxide solutions.Reactions of I were studied in ethanol and isotop

Full text of DOI:10.1021/ja00346a048

Products guided by the article

Product name:α-Chlor-α-Tritio-β,β,β-trifluoraethylbenzol

Cas No:58852-20-3

R&D Labs maybe for 58852-20-3

Suzhou Health Chemicals Co., Ltd.

website:http://www.healthchems.com

Contact:13776257979

Address:No. 338, Jingang Avenue,
SAGECHEM LIMITED

website:http://www.sagechem.com

Contact:+86-571-86818502

Address:Room C1301, New Youth Plaza, 8 Jia Shan Road, Hangzhou, China
Jinzhou Jiutai Pharmaceutical Co.,Ltd

Contact:+86-0416-5179890

Address:No.41, Taianli, Taihe District, Jinzhou, Liaoning
Anhui Charm Imp.&Exp.Co., Ltd

website:http://www.chinacharm.cn/

Contact:86 551 5316260

Address:No. 211,XiangZhang Road,Hefei City,Anhui Province,China
JIANGXI XINXIN CHEMICAL CO., LTD.

Contact:86-15957176628

Address:INDUSTRY ROAD 1, INDUSTRIAL PARK, HEKOU TOWN,YANSHAN COUNTY, JIANGXI PROVINCE, CHINA

Relevant to this article

6-(Aryldiazenyl)pyrazolo[1,5-a]pyrimidines as Strategic Intermediates for the Synthesis of Pyrazolo[5,1-b]purines

Doi:10.1021/acs.joc.6b02431
(2016)
Doi:10.1016/0040-4020(75)80049-4
(1975)
Diversity-Oriented Synthesis of Coumarin-Linked Benzimidazoles via a One-Pot, Three-Step, Intramolecular Knoevenagel Cyclization

Doi:10.1021/acscombsci.7b00004
(2017)
Novel NMR chiral solvating agents derived from (1R,2R)-diaminocyclohexane: synthesis and enantiodiscrimination for chiral carboxylic acids

Doi:10.1016/j.tetasy.2006.03.011
(2006)
Doi:10.1055/s-1978-24703
(1978)
Doi:10.1039/DT9760000081
()

Article Doi