Continue refining the compounds through an iterative process of synthesis, testing, and SAR analysis. Adjust the modifications as necessary to improve selectivity and efficacy.
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(6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-((R)-1-(4-dimethylaminobenzyl)pyrrolidin-3-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
1-(5-mercapto-[1,3,4]thiadiazol-2-yl)-3-phenylurea
