Lead Compound Selection

Medicinal chemistry Characterization Optimization Molecular modeling Chemical characterization Biological testing Chemical modification Purification Starting Material Structure-Activity Relationship (SAR) Analysis Preclinical and Clinical Studies Chemical Synthesis Biological Assays Animal Studies Structure-Activity Relationship (SAR) Studies Clinical Trials High-Throughput Screening Clinical Development Post-Marketing Surveillance Literature Review Safety and Toxicity Assessment In Vivo Studies Regulatory Considerations Subsequent Transformations Hit Identification FDA Approval Structure Optimization Formulation Development Virtual Screening Toxicity and ADME Studies Regulatory Approval Preclinical Studies Market Launch Design and Synthesis Animal Models Structure-Activity Relationship Analysis Synthesis and Testing Iterative Optimization Characterization and Purification Scale-Up and Formulation Toxicity and Safety Evaluation Publication and Reporting Patent Application Further Optimization Molecular Modeling and Computational Chemistry Molecular Dynamics Simulations Patent and Regulatory Considerations Scale-Up Production Pharmacokinetic and Toxicity Studies Cell-Based Assays