Chemists synthesize the designed compounds and test them in vitro to assess their inhibitory activity against caspase-1. Biological assays can help determine the potency and specificity of the inhibitors.
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2-(4-isopropyl-3-methyl-phenoxy)-phenylamine
(6R,12aR)-6-benzo[1,3]dioxol-5-yl-2-((R)-1-(4-dimethylaminobenzyl)pyrrolidin-3-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
