TBAF

Synthesis Catalyst Reduction Hydrolysis Phenacyl esters Thiol Tetrahydrofuran (THF) Oxidation-reduction reaction Deprotecting reagent Base catalyzed hydrolysis Fluorinated product Protecting groups TPAP ZnCl2 Li, NH3(l) DDQ TsCl Py. N-phenyl pyrazoline adduct 3J coupling constant X-ray diffraction analysis Chemoselective Retrosynthetic analysis Purification and characterization Scale-up and optimization Final steps Stereochemical Control Metal-free 5-Exo-Dig Cyclization Tigliane Diterpenoid Core Synthesis Introduction of the Phenol Group Experimental terms Propargyl urea Nitroarenes diaryl thioethers PhSTMS denitrative substitution mild and neutral conditions Metal free α-keto amides