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CAS No.: | 10527-64-7 |
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Name: | 2-(4-benzhydrylpiperazin-1-yl)ethanol |
Article Data: | 12 |
Molecular Structure: | |
Formula: | C19H24N2O |
Molecular Weight: | 296.412 |
Synonyms: | Benzenamine,4-(1,3,2-dioxaborolan-2-yl)-N,N-diphenyl;4-benzhydryl-1-piperazineethanol;2-(4-benzhydryl-piperazine)-ethan-1-ol;4-diphenylmethyl-1-piperazineethanol;2-(4-benzhydrylpiperazinyl)ethanol;1-diphenylmethyl-4-(2-hydroxyethyl)piperazine;2-[4-(diphenylmethyl)piperazine-1-yl]ethanol;1-benzhydryl-4-(2-hydroxyethyl)piperazine;2-((4-diphenylamino)phenyl)[1,3,2]dioxaborolane; |
Density: | 1.115±0.06 g/cm3(Predicted) |
Boiling Point: | 180 °C(Press: 0.01 Torr) |
PSA: | 26.71000 |
LogP: | 2.26170 |
1-(2-hydroxyethyl)piperazine
Bromodiphenylmethane
1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
Conditions | Yield |
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With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 3.5h; | 85.4% |
diphenylmethylpiperazine
2-bromoethanol
1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 60℃; | 66% |
With potassium carbonate In acetone at 60℃; | 55% |
1-(2-hydroxyethyl)piperazine
diphenylchloromethane
1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
Conditions | Yield |
---|---|
Stage #1: 1-(2-hydroxyethyl)piperazine With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 20℃; Stage #2: diphenylchloromethane In N,N-dimethyl-formamide at 20 - 70℃; | 37% |
With sodium carbonate; xylene | |
at 130℃; |
1-(2-hydroxyethyl)piperazine
potassium carbonate
Bromodiphenylmethane
1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
Conditions | Yield |
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In N,N-dimethyl-formamide | 21.9 g (84.2%) |
In N,N-dimethyl-formamide | 21.9 g (84.2%) |
diphenylmethylpiperazine
2-chloro-ethanol
1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide; toluene at 20℃; Reflux; | |
With potassium carbonate In N,N-dimethyl-formamide; toluene Reflux; |
1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
methyl (E)-3-aminocrotonate
Conditions | Yield |
---|---|
With triethylamine In chloroform at 50 - 60℃; Solvent; Temperature; | 86.3% |
1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
1-diphenylmethyl-4-(2-chloroethyl)piperazine
Conditions | Yield |
---|---|
With thionyl chloride In toluene at 60℃; for 3h; | 84% |
With thionyl chloride; benzene |
1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
2-(4-diphenylmethyl-1-piperazinyl)ethyl acetoacetate
Conditions | Yield |
---|---|
at 20 - 80℃; for 6h; Temperature; | 72.3% |
With triethylamine In chloroform for 10h; Ambient temperature; | 59.1% |
at 70 - 80℃; for 2h; | 739.8 g |
1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
cyanoacetic acid
Conditions | Yield |
---|---|
With dicyclohexyl-carbodiimide In tetrahydrofuran at 55℃; | 56% |
1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
3-[2-(4-benzhydryl-piperazino)-ethoxy]-propan-1-ol
Conditions | Yield |
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With thionyl chloride; benzene anschl. Erwaermen mit der Mononatrium-Verbindung des Propan-1,3-diols auf 100grad; |