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Basic Information
CAS No.: 1081-05-6
Name: 5-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
Molecular Structure:
Molecular Structure of 1081-05-6 (5-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER)
Formula: C10H9 Cl N2 O2
Molecular Weight: 224.647
Synonyms: 5-Chlor-3-ethoxycarbonyl-indazol;QC-9439;5-Chloro-1H-indazole-3-carboxylic acid ethyl ester;
Density: 1.391±0.06 g/cm3(Predicted)
Melting Point: 223 °C
Boiling Point: 386.5±22.0 °C(Predicted)
PSA: 54.98000
LogP: 2.39300
Synthetic route
64-17-5

ethanol

1077-95-8

5-chloro-1H-indazole-3-carboxylic acid

1081-05-6

5-chloro-1(2)H-indazole-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
With sulfuric acid at 100℃; for 5h;
17630-76-1

5-chloroindole 2,3-dione

1081-05-6

5-chloro-1(2)H-indazole-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sodium hydroxide / water / 0.5 h / 50 °C
1.2: 1 h / 0 °C
1.3: 18 h / 0 - 20 °C
2.1: sulfuric acid / 5 h / 100 °C
View Scheme
1081-05-6

5-chloro-1(2)H-indazole-3-carboxylic acid ethyl ester

1711-06-4

3-Methylbenzoyl chloride

1448314-59-7

5-chloro-1-(3-methylbenzoyl)-1H-indazole-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 4h;27%
10400-19-8

3-pyridinecarbonyl chloride

1081-05-6

5-chloro-1(2)H-indazole-3-carboxylic acid ethyl ester

5-Chloro-1-(pyridine-3-carbonyl)-1H-indazole-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
With pyridine Heating;
3282-30-2

pivaloyl chloride

1081-05-6

5-chloro-1(2)H-indazole-3-carboxylic acid ethyl ester

5-Chloro-1-(2,2-dimethyl-propionyl)-1H-indazole-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
With pyridine Heating;
403-43-0

4-fluorobenzoyl chloride

1081-05-6

5-chloro-1(2)H-indazole-3-carboxylic acid ethyl ester

fluoro-5 N1-chlorobenzoyl 1H-indazole carboxylate d'ethyle-3

Conditions
ConditionsYield
With pyridine Heating;
98-88-4

benzoyl chloride

1081-05-6

5-chloro-1(2)H-indazole-3-carboxylic acid ethyl ester

1-Benzoyl-5-chloro-1H-indazole-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
With pyridine Heating;
122-01-0

4-chloro-benzoyl chloride

1081-05-6

5-chloro-1(2)H-indazole-3-carboxylic acid ethyl ester

chloro-5 N1-chlorobenzoyl 1H-carboxylate d'ethyle-3

Conditions
ConditionsYield
With pyridine Heating;
38835-18-6

naproxen chloride

1081-05-6

5-chloro-1(2)H-indazole-3-carboxylic acid ethyl ester

5-Chloro-1-[2-(6-methoxy-naphthalen-2-yl)-propionyl]-1H-indazole-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
With pyridine Heating;
1081-05-6

5-chloro-1(2)H-indazole-3-carboxylic acid ethyl ester

75-36-5

acetyl chloride

1-Acetyl-5-chloro-1H-indazole-3-carboxylic acid ethyl ester

Conditions
ConditionsYield
With pyridine Heating;
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    Business Type:Lab/Research institutions

    Tel:+86-21-53535353

    Address:28F No.900 huaihai Road Shanghai China

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  • 5-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER

  • Casno:

    1081-05-6

    5-CHLORO-1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrated por

    Shanghai fine pharma co., Ltd. is a professional enterprise with chemical reagents and fine chemical products development, development and trade. The company has a sound research a

  • Shanghai Run-Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-21-31576854/57171705 / 57171706

    Address:second floor, building 3, No.999, jiangyue Road, minghang District, Shanghai, China

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  • 1H-Indazole-3-carboxylicacid, 5-chloro-, ethyl ester

  • Casno:

    1081-05-6

    1H-Indazole-3-carboxylicacid, 5-chloro-, ethyl ester

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    1H-Indazole-3-carboxylicacid, 5-chloro-, ethyl ester Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier like DHL or Fedx. Port

    Nanjing Raymon Biotech Co., Ltd. is specialized in developing and marketing middle & high level pharmaceutical intermediates. We are supplying different categories of high-quality

  • Nanjing Raymon Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-025-52181296

    Address:Block B, No. 918, Shuanglong Avenue

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  • 5-Chloro-1H-indazole-3-carboxylic acid ethyl ester

  • Casno:

    1081-05-6

    5-Chloro-1H-indazole-3-carboxylic acid ethyl ester

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

    Hunan Runhui Chem Co., Ltd. is a comprehensive Fine chemicals and Pharmaceuticals Intermediates supplier in China , Established in Changsha City of Hunan province registered capit

  • Hunan Longxianng Runhui Trading Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-731-85570686

    Address:29 Floor,Changsheng Upper Strata,Furong District,China

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  • 1081-05-6

  • Casno:

    1081-05-6

    1081-05-6

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Supply top quality products with a reasonable price Application:api

    Hebei Ruishun Trade Co.,Ltd registered capital one million, we have a production of pharmaceutical raw materials, pharmaceutical raw materials factory reagent r&d center, we do

  • Hebei Ruishun Trade Co.,Ltd

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-311-68037669

    Address:WanDa commerce building ,yuhua district

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  • ethyl 5-chloro-1H-indazole-3-carboxylate

  • Casno:

    1081-05-6

    ethyl 5-chloro-1H-indazole-3-carboxylate

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    high purity Application:Drug intermediates Materials intermediates and active molecules

    Novachemistry offers a broad range of specialty chemicals and customized synthesis services to a range of pharmaceutical, agrochemical and biochemical industries. Novachemistry has

  • NovaChemistry

    United Kingdom  |  Contact Details

    Business Type:Trading Company

    Tel:+44 (0)208 191 7890

    Address:Unit11, Ark Business Centre, Gorden Road, Loughborough, United Kingdom

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