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13575-41-2

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Basic Information
CAS No.: 13575-41-2
Name: Thiazolo[4,5-b]pyridin-2-amine
Article Data: 3
Molecular Structure:
Molecular Structure of 13575-41-2 (Thiazolo[4,5-b]pyridin-2-amine)
Formula: C6H5N3S
Molecular Weight: 151.192
Synonyms: MD-0359;
Density: 1.485
Melting Point: 118.1 °C
Boiling Point: 329℃
Flash Point: 153℃
PSA: 80.77000
LogP: 1.20360
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Synthetic route
14294-11-2

2-pyridylthiourea

13575-41-2

[1,3]thiazolo[4,5-b]pyridin-2-amine

Conditions
ConditionsYield
With bromine In chloroform Heating;57%
504-29-0

2-aminopyridine

333-20-0

potassium thioacyanate

13575-41-2

[1,3]thiazolo[4,5-b]pyridin-2-amine

Conditions
ConditionsYield
With bromine; acetic acid
504-29-0

2-aminopyridine

methyl halide

methyl halide

13575-41-2

[1,3]thiazolo[4,5-b]pyridin-2-amine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 64 percent / aq. HCl / 6 h / Heating
2: 57 percent / Br2 / CHCl3 / Heating
View Scheme
13534-99-1

2-Amino-3-bromopyridine

13575-41-2

[1,3]thiazolo[4,5-b]pyridin-2-amine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetone / 14 h / 60 °C
2: sodium hydroxide; water / methanol / 2 h / 70 °C
3: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.14 h / 90 °C
View Scheme

C13H10BrN3OS

13575-41-2

[1,3]thiazolo[4,5-b]pyridin-2-amine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydroxide; water / methanol / 2 h / 70 °C
2: sodium hydride / mineral oil; N,N-dimethyl-formamide / 0.14 h / 90 °C
View Scheme

1-(3-bromopyridin-2-yl)thiourea

13575-41-2

[1,3]thiazolo[4,5-b]pyridin-2-amine

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 90℃; for 0.14h;8.6 g
6066-82-6

1-hydroxy-pyrrolidine-2,5-dione

13575-41-2

[1,3]thiazolo[4,5-b]pyridin-2-amine

1-{([1,3]thiazolo[4,5-b]pyridin-2-yldiazenyl)oxy}-pyrrolidine-2,5-dione

Conditions
ConditionsYield
Stage #1: [1,3]thiazolo[4,5-b]pyridin-2-amine With hydrogenchloride; sodium nitrite at 0 - 5℃;
Stage #2: 1-hydroxy-pyrrolidine-2,5-dione With sodium hydroxide at 0 - 5℃; pH=8 - 10;		55%
524-38-9

N-hydroxyphthalimide

13575-41-2

[1,3]thiazolo[4,5-b]pyridin-2-amine

2-{([1,3]thiazolo[4,5-b]pyridin-2-yldiazenyl)oxy}-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
Stage #1: [1,3]thiazolo[4,5-b]pyridin-2-amine With hydrogenchloride; sodium nitrite at 0 - 5℃;
Stage #2: N-hydroxyphthalimide With sodium hydroxide at 0 - 5℃; pH=8 - 10;		52%
6066-82-6

1-hydroxy-pyrrolidine-2,5-dione

13575-41-2

[1,3]thiazolo[4,5-b]pyridin-2-amine

1-{[1,3]thiazolo[4,5-b]pyridin-2-yloxy}pyrrolidine-2,5-dione

Conditions
ConditionsYield
Stage #1: [1,3]thiazolo[4,5-b]pyridin-2-amine With hydrogenchloride; sodium nitrite at 0 - 5℃;
Stage #2: 1-hydroxy-pyrrolidine-2,5-dione With sodium hydroxide at 0 - 5℃; pH=10 - 12;		51%
13575-41-2

[1,3]thiazolo[4,5-b]pyridin-2-amine

273-98-3

thiazolo(4,5-b)pyridine

Conditions
ConditionsYield
With isopentyl nitrite In tetrahydrofuran at 65℃; for 4h;46.6%
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  • CAS:13575-41-2 thiazolo[4,5-b]pyridin-2-amine CAS NO.13575-41-2

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  • Shandong Haiyun Pharmaceutical Technology Co.Ltd

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    Tel:0546-3658889

    Address:Hekou Dongying Shandong China

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  • Thiazolo[4,5-b]pyridin-2-amine

  • Casno:

    13575-41-2

    Thiazolo[4,5-b]pyridin-2-amine

    Min.Order: 0 Metric Ton

    FOB Price:  USD $ 0.0-0.0

    Storage:Low temperature dry and shady Package:according to the request of customer Application:only for research Transportation:according to the request of customer

    Jinan Trio PharmaTech Co., Ltd. locates at one of the largest National Technical Integrated Drug Discovery Platforms in the High-Tech Zone

  • Jinan Trio PharmaTech Co., Ltd

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    Business Type:Lab/Research institutions

    Tel:86-531-88811783；86-531-88806178；+(0)13153010282

    Address:2766 Yingxiu Road, Jinan High-Tech Zone, China

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  • Thiazolo[4,5-b]pyridin-2-amine

  • Casno:

    13575-41-2

    Thiazolo[4,5-b]pyridin-2-amine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Package:1g,5g,10g

    Sphinx Scientific Laboratory Corporation (SSL) is a rapidly growing manufacturer of high quality pharmaceutical intermediates, novel chemical and pharmaceutical building blocks,

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    Address:Tianda high-tech Park. No.80,the 4th Avenue

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  • THIAZOLO[4,5-B]PYRIDIN-2-AMINE

  • Casno:

    13575-41-2

    THIAZOLO[4,5-B]PYRIDIN-2-AMINE

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:yellow to white solid Storage:keep sealed and keep from direct light Package:According client's requirements Application:Phar

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    Business Type:Other

    Tel:86-531-8233381 86-18678657237

    Address:Room 302,Building 1,Union Fortune Square, No. 2117,Tianchen Road,High-tech Zone,Jinan,Shandong,China

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  • Thiazolo[4,5-b]pyridin-2-amine

  • Casno:

    13575-41-2

    Thiazolo[4,5-b]pyridin-2-amine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Manufacturer,strong R&D,professional team Storage:Store in a cool, dry place. Store in a tightly closed container. Package:according to your requirement Application:ZhiShang Chemical is owned by ZhiShang Group, is a professional new-type chemicals en

  • Chemical Co.Ltd

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  • Thiazolo[4,5-b]pyridin-2-amine

  • Casno:

    13575-41-2

    Thiazolo[4,5-b]pyridin-2-amine

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    high purity Application:Drug intermediates Materials intermediates and active molecules

    Novachemistry offers a broad range of specialty chemicals and customized synthesis services to a range of pharmaceutical, agrochemical and biochemical industries. Novachemistry has

  • NovaChemistry

    United Kingdom  |  Contact Details

    Business Type:Trading Company

    Tel:+44 (0)208 191 7890

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Specification

The Thiazolo[4,5-b]pyridin-2-amine, with the CAS registry number 13575-41-2, is also known as 2-Aminothiazolo[4,5-b]pyridine.It belongs to the product Pyridines. This chemical's molecular formula is C6H5N3S and molecular weight is 151.19. What's more, Its systematic name is Thiazolo[4,5-b]pyridin-2-amine.Physical properties about Thiazolo[4,5-b]pyridin-2-amine are:(1)Density: 1.485; (2)Melting point: 239-242 ℃; (3)Boiling point: 329 ℃; (4)Flash point: 153℃.