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CAS No.: | 14916-80-4 | |||
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Name: | 3-Octyn-1-ol | |||
Article Data: | 21 | |||
Molecular Structure: | ||||
Formula: | C8H14 O | |||
Molecular Weight: | 126.199 | |||
Synonyms: | NSC 67251 | |||
EINECS: | 238-986-1 | |||
Density: | 0.876 | |||
Melting Point: | -39°C (estimate) | |||
Boiling Point: | 86 - 88 C at 9 mm Hg | |||
Flash Point: | > 110 C | |||
Solubility: | Soluble | clear to yellowish oily liquid | ||
Hazard Symbols: | ||||
Risk Codes: | R36/37/38 | |||
Safety: | S24 25 26;S37/39 | |||
Transport Information: | 170kgs | |||
PSA: | 20.23000 | |||
LogP: | 1.56240 |
oct-3-yn-1-ol
Conditions | Yield |
---|---|
With acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium nitrite at 20℃; for 18h; Green chemistry; chemoselective reaction; | 93% |
2-(3-octyn-1-yloxy)tetrahydro-2H-pyran
oct-3-yn-1-ol
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In methanol; water at 23℃; Inert atmosphere; | 86% |
Conditions | Yield |
---|---|
With iron(III)-acetylacetonate In diethyl ether; ammonia from -30 to 20 deg C, 15 h; | 65% |
Conditions | Yield |
---|---|
With lithium; ferric nitrate In tetrahydrofuran; ammonia for 3h; | 62.2% |
Stage #1: 3-Butyn-1-ol With lithium amide; ammonia; ferric nitrate at -50℃; for 1h; Stage #2: 1-bromo-butane for 2h; Further stages.; | 26.6% |
With lithium amide In ammonia | |
With N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium 1.) THF, hexane, -23 deg C --> r.t., 30 min, 2.) -23 deg C, 4 h; Yield given. Multistep reaction; | |
With lithium amide; ammonia; ferric nitrate |
Conditions | Yield |
---|---|
With ammonia |
Conditions | Yield |
---|---|
(i) Na, liq. NH3, Fe(NO3)3, (ii) /BRN= 102378/; Multistep reaction; | |
Stage #1: hex-1-yne With ethylmagnesium bromide In tetrahydrofuran Reflux; Stage #2: oxirane In tetrahydrofuran at 20℃; |
1-vinyloxy-oct-3-yne
oct-3-yn-1-ol
Conditions | Yield |
---|---|
With hydrogenchloride |
Conditions | Yield |
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In benzene 12 h, RT; 4 h, reflux; |
Conditions | Yield |
---|---|
With lithium 1) THF, reflux, 2) DMSO, 60 - 65 deg C, 3h; Yield given. Multistep reaction; |
IUPAC Name: Oct-3-yn-1-ol
Molecular Formula C8H14O
Molecular Weight 126.20
Index of Refraction: 1.458
Flash Point: 106 ºC
EINECS: 238-986-1
Density 0.880 g/mL at 25 °C(lit.)}
Refractive index 1.4555-1.4575
Enthalpy of Vaporization: 52.61 kJ/mol
Boiling Point: 216 °C at 760 mmHg
Vapour Pressure: 0.031 mmHg at 25°C
Appearance: Colorless - yellow Liquid
Chemical Stability: Stable under normal temperatures and pressures
Product Categories: Miscellaneous ; Acetylenes ; Acetylenic alcohols & Their derivatives ; Alkynes ; Internal ; Organic building blocks
Synonyms: 3-Octyne-1-ol ; 3-Octyn-1-ol ; Timtec-bb SBB009106 ; Octynol ; N-butyl-2-hydroxyethylacetylene ; Oct-3-yn-1-ol ; 3-Octyn-1-ol 98% ; 1-Butyl-2-(2-hydroxyethyl)acetylene
Following is the molecular structure of Oct-3-yn-1-ol (14916-80-4):
Safety Information of Oct-3-yn-1-ol (14916-80-4):
Hazard Codes: Xi
Xi :Irritant
Risk Statements: 36/37/38
36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36-37/39
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37/39: Wear suitable gloves and eye/face protection
WGK Germany: 3
Potential Health Effects of Oct-3-yn-1-ol (14916-80-4):
1.Eye: Causes eye irritation.
2.Skin: Causes skin irritation. May be harmful if absorbed through the skin.
3.Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed.
4.Inhalation: Causes respiratory tract irritation. May be harmful if inhaled
First Aid Measures of Oct-3-yn-1-ol (14916-80-4):
1.Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
2.Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
3.Ingestion: Get medical aid. Wash mouth out with water.
4.Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
5.Notes to Physician: Treat symptomatically and supportively.
Fire Fighting Measures of Oct-3-yn-1-ol (14916-80-4):
1.General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
2.Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Accidental Release Measures of Oct-3-yn-1-ol (14916-80-4):
1.General Information: Use proper personal protective equipment as indicated in Section 8.
2.Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.
Handling and Storage of Oct-3-yn-1-ol (14916-80-4):
1.Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
2.Storage: Store in a cool, dry place. Store in a tightly closed container