Welcome to LookChem.com Sign In|Join Free
  • or
Home > Pharmaceutical > 22246 > 

22246-18-0

Basic Information
CAS No.: 22246-18-0
Name: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Molecular Structure:
Molecular Structure of 22246-18-0 (3,4-Dihydro-7-hydroxy-2(1H)-quinolinone)
Formula: C9H9NO2
Molecular Weight: 163.17
Synonyms: 3,4-Dihydrogen-7-Hydroxy-2(1H)-Quinolinone;7-Hydroxy-3,4-dihydro-2(1H)Quinolineone;7-Hydroxy-3,4-Dihydro-2(1H)Quinoliunone;2(1H)-Quindinone,3,4-dohydro-7Hydroxy;7-Hydroxy-3,4-dihydro-2-quinolinone;7-Hydroxy-3,4-dihydro-2(1H)Quinolinone;7-(4-bromo-butoxy)-3,4-dihydro-1H-quinolin-2-one;7-hydroxy-3,4-dihydroquinazolone;7-Hydroxy-3,4-dihydro-1H-quinolin-2-one;3,4-dihydro-7-hydroxycarbostyril;7-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone;7-hydroxy-3, 4-dihydro-2 (1H)-quinolinone;7-Hydroxy-2-Oxo-3,4-Dihydroquinoline;
EINECS:
Density: 1.282 g/cm3
Melting Point: 233-237 °C
Boiling Point: 403.7 °C at 760 mmHg
Flash Point: 198 °C
Solubility:
Appearance: Pale yellow powder
Hazard Symbols: HarmfulXn, IrritantXi
Risk Codes: 22-43
Safety: S36/37
Transport Information:
PSA: 49.33000
LogP: 1.41490
Synthetic route
50297-40-0

3-chloro-N-(3-hydroxyphenyl)propanamide

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
With aluminum (III) chloride In N,N-dimethyl-formamide at 90 - 150℃; for 6h; Cooling with ice;88%
Stage #1: 3-chloro-N-(3-hydroxyphenyl)propanamide With aluminum (III) chloride at 210℃; for 0.5h;
Stage #2: With water at 20℃;
76%
With aluminum (III) chloride In N,N-dimethyl acetamide at 130 - 140℃;68%
21261-76-7

3-chloro-N-(3-methoxyphenyl)propionamide

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
aluminum (III) chloride In N,N-dimethyl acetamide at 140 - 150℃; for 2.75h; Friedel Crafts Alkylation;82%
With aluminium trichloride; N,N-dimethyl acetamide at 150 - 160℃; for 2h; Friedel-Crafts reaction;61.5%
With aluminum (III) chloride In N,N-dimethyl acetamide at 0 - 150℃; for 2h;54%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
With ammonium formate on silica gel; zinc In carbon dioxide at 50℃; under 90009 Torr; Autoclave; liquid CO2;78%

4-benyzloxy-2-nitrobenzenediazonium tetrafluoroborate

292638-85-8

acrylic acid methyl ester

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
Stage #1: 4-benyzloxy-2-nitrobenzenediazonium tetrafluoroborate; acrylic acid methyl ester With palladium diacetate In 1,4-dioxane at 25℃; for 6h; Heck reduction-cyclisation-debenzylation reaction;
Stage #2: With hydrogen; palladium diacetate; pyrographite In 1,4-dioxane at 50℃; for 24h; Heck reduction-cyclisation-debenzylation reaction;
66%
21261-76-7

3-chloro-N-(3-methoxyphenyl)propionamide

A

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

B

30389-33-4

5-hydroxycarbostyril

Conditions
ConditionsYield
Stage #1: N-(3-methoxyphenyl)-3-chloropropionamide; aluminum (III) chloride at 155 - 165℃; for 4h;
Stage #2: With methanol; sodium hydroxide In water at 20℃; for 1h; pH=7; Product distribution / selectivity; Heating / reflux;
A 62.3%
B n/a
Stage #1: N-(3-methoxyphenyl)-3-chloropropionamide With N,N-dimethyl acetamide; aluminum (III) chloride In water at 95 - 165℃; for 5.5h;
Stage #2: With methanol; sodium hydroxide In water at 20℃; for 1h; pH=7; Product distribution / selectivity; Heating / reflux;
A 61.3%
B n/a
Stage #1: N-(3-methoxyphenyl)-3-chloropropionamide; aluminum (III) chloride In water at 95 - 165℃; for 5.5h;
Stage #2: With methanol; sodium hydroxide In water at 20℃; for 1h; pH=7; Product distribution / selectivity; Heating / reflux;
A 61.3%
B n/a
aluminum chloride powder

aluminum chloride powder

21261-76-7

3-chloro-N-(3-methoxyphenyl)propionamide

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
In ice-H2O55%
22246-17-9

7-methoxy-2-oxo-1,2,3,4-tetrahydroquinoline

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
With hydrogen bromide
50297-40-0

3-chloro-N-(3-hydroxyphenyl)propanamide

A

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

B

5-hydroxy-3,4-dihydro-1H-quinolin-2-one

5-hydroxy-3,4-dihydro-1H-quinolin-2-one

Conditions
ConditionsYield
With aluminium trichloride beim Schmelzen;
536-90-3

m-Anisidine

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 96 percent / NaHCO3 / CH2Cl2 / 4 h / 20 °C
2: 61.5 percent / N,N-dimethylacetamide; aluminium trichloride / 2 h / 150 - 160 °C
View Scheme
Multi-step reaction with 2 steps
1: 95 percent / aq. K2CO3 / acetone / 1 h / 0 °C
2: 4 percent / AlCl3 / chlorobenzene / 6 h / 120 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium carbonate / toluene / 2 h / 40 - 65 °C
2: aluminum (III) chloride / N,N-dimethyl acetamide / 140 - 150 °C
View Scheme
Multi-step reaction with 2 steps
1: pyridine / tetrahydrofuran / 0 - 20 °C
2: aluminum (III) chloride; N,N-dimethyl acetamide / 4 h / 140 °C
View Scheme
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / toluene / 2 h / 50 °C
2: aluminum (III) chloride / N,N-dimethyl acetamide / 2 h / 0 - 150 °C
View Scheme
103986-96-5

methyl (E)-3-(4′-methoxy-2′-nitrophenyl)acrylate

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Raney nickel; ethanol / Hydrogenation
2: aqueous hydrobromic acid
View Scheme
625-36-5

2-chloropropionyl chloride

591-27-5

m-Hydroxyaniline

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

4-hydroxy-2-nitrobenzenediazonium tetrafluoroborate

292638-85-8

acrylic acid methyl ester

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
Stage #1: 4-hydroxy-2-nitrobenzenediazonium tetrafluoroborate; acrylic acid methyl ester With sodium acetate; palladium diacetate In methanol at 20℃; for 12h; Mizoroki-Heck reaction; Inert atmosphere;
Stage #2: With hydrogen; pyrographite In methanol at 20℃; under 750.075 Torr; for 24h;
Stage #3: With hydrogenchloride In methanol; water
360 mg
7403-75-0

N-(4-hydroxy-2-nitrophenyl)-acetamide

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: boron trifluoride - methanol (1/1) / methanol / 5 h / Inert atmosphere; Reflux
1.2: 0.33 h / -15 - 0 °C
2.1: sodium acetate; palladium diacetate / methanol / 12 h / 20 °C
3.1: pyrographite; hydrogen / methanol / 24 h / 750.08 Torr
View Scheme

C10H9NO5

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
With hydrogen; pyrographite In methanol under 750.075 Torr; for 24h;360 mg
591-27-5

m-Hydroxyaniline

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate / acetonitrile / 0 °C
2: aluminum (III) chloride / dichloromethane
View Scheme
Multi-step reaction with 2 steps
1: sodium hydroxide / 2 h / 25 °C / pH 9
2: boron trifluoride diethyl etherate / toluene / 2 h / 60 °C
View Scheme
Multi-step reaction with 2 steps
1.1: sodium hydrogencarbonate / dichloromethane / 0.5 h / 20 °C / Inert atmosphere
1.2: 2 h / 20 °C / Inert atmosphere
2.1: aluminum (III) chloride / N,N-dimethyl acetamide / 4 h / 70 - 140 °C
View Scheme

C9H11NO3

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

Conditions
ConditionsYield
With boron trifluoride diethyl etherate In toluene at 60℃; for 2h; Temperature;
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

18162-48-6

tert-butyldimethylsilyl chloride

1427053-51-7

7-(tert-butyl-dimethylsilanyloxy)-3,4-dihydro-1H-quinolin-2-one

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 0℃;99.4%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

58196-33-1

7-hydroxy-1,2,3,4-tetrahydroquinoline

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran Inert atmosphere; Cooling with ice; Reflux;98%
With sodium tetrahydroborate In tetrahydrofuran at 0℃; Reflux;98%
With lithium aluminium tetrahydride In tetrahydrofuran Cooling with ice; Reflux;95%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

766-80-3

1-bromomethyl-3-chlorobenzene

1458219-01-6

7-((3-chlorobenzyl)oxy)-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 60℃; for 18h;97%
With potassium carbonate In acetonitrile for 8h; Reflux;68%
With potassium hydroxide In ethanol for 5h; Reflux;32%
6940-78-9

4-chlorobutyl bromide

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

120004-79-7

7-(4-chlorobutoxy)-3,4-dihydroquinoline-2(1H)-one

Conditions
ConditionsYield
With lithium hydroxide In water; N,N-dimethyl-formamide at 40 - 50℃; for 3h; Reagent/catalyst; Solvent; Sealed tube; Large scale;95%
With potassium carbonate; polyethylene glycol-400 In water; acetone at 20℃; for 15.1667 - 16.1667h;94%
With potassium carbonate In N,N-dimethyl-formamide at 20 - 30℃; for 24h; Solvent; Temperature; Large scale;93.2%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

613-54-7

2-Bromo-2'-acetonaphthone

1303566-73-5

7-[2-(naphthalen-2-yl)-2-oxoethoxy]-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: 2-Bromo-2'-acetonaphthone In N,N-dimethyl-formamide at 20℃; for 24h;
95%
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h;
Stage #2: 2-Bromo-2'-acetonaphthone In N,N-dimethyl-formamide at 20℃; for 24h;
88%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

29882-07-3

4-chlorobutanal dimethyl acetal

1359159-57-1

7-(4,4-dimethoxybutoxy)-3,4-dihydro-1H-quinolin-2-one

Conditions
ConditionsYield
With tetrabutylammomium bromide; potassium carbonate In dimethyl sulfoxide at 115℃; for 4h;95%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

70500-72-0

7-hydroxy-1H-quinolin-2-one

Conditions
ConditionsYield
With palladium 10% on activated carbon; water; oxygen; acetic acid at 110 - 116℃; for 18h; Reagent/catalyst; Temperature;94.2%
With palladium 10% on activated carbon In decalin at 180℃; for 8h;90.9%
With 2,3-dicyano-5,6-dichloro-p-benzoquinone In tetrahydrofuran at 66℃; for 4h; Catalytic behavior; Concentration; Solvent; Temperature;89%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

100-07-2

4-methoxy-benzoyl chloride

7-(4-methoxybenzoyloxy)-3,4-dihydro-1H-quinolin-2-one

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 5h;93.3%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

1,4-dichlorobutane-d8

C13H8(2)H8ClNO2

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 80℃; for 3h; Inert atmosphere;92%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

C14H19Cl3N2*ClH

129722-12-9

aripiprazole

Conditions
ConditionsYield
With potassium carbonate In water at 99℃; for 5h; Reagent/catalyst; Temperature;91.4%
110-52-1

1,4-dibromo-butane

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

129722-34-5

7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinone

Conditions
ConditionsYield
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With potassium carbonate In water; acetone at 20℃; for 1h;
Stage #2: 1,4-dibromo-butane In water; acetone at 20℃; for 16h;
91%
With potassium iodide; sodium hydroxide In acetonitrile at 30℃; for 16h;85%
With sodium hydroxide In ethanol for 2.5h; Heating;83%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

110-56-5

1,4-dichlorobutane

120004-79-7

7-(4-chlorobutoxy)-3,4-dihydroquinoline-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In propan-1-ol for 8 - 10h; Product distribution / selectivity; Heating / reflux;91%
With potassium carbonate; sodium sulfate; Aliquat 336 In toluene for 14h; Product distribution / selectivity; Heating / reflux;75%
With potassium carbonate In ISOPROPYLAMIDE at 90 - 95℃; for 15 - 16h;75%
With potassium carbonate In acetonitrile for 22h; Product distribution / selectivity; Heating / reflux;74%
With potassium carbonate In propan-1-ol; isopropyl alcohol for 19h; Product distribution / selectivity; Heating / reflux;66%
629-03-8

1 ,6-dibromohexane

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

1303529-03-4

7-((6-bromohexyl)oxy)-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With potassium carbonate In water; acetone at 20℃; for 1h;
Stage #2: 1 ,6-dibromohexane In water; acetone at 20℃; for 16h;
91%
With potassium carbonate In acetonitrile at 60 - 65℃; Inert atmosphere;56.8%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

129722-34-5

7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinone

7-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-7-oxy)butoxy)-3,4-dihydroquinoline-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80℃;90.9%
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With sodium hydroxide In methanol for 2h; Heating;
Stage #2: 7-(4-bromobutoxy)-3,4-dihydro-2(1H)-quinolinone In N,N-dimethyl-formamide at 20℃; Further stages.;
16.8 g
With potassium hydroxide In ethanol Reflux;
111-24-0

1,5-dibromo-pentane

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

63309-41-1

7-((5-bromopentyl)oxy)-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With potassium carbonate In water; acetone at 20℃; for 1h;
Stage #2: 1,5-dibromo-pentane In water; acetone at 20℃; for 16h;
90%
With potassium carbonate In acetonitrile at 60 - 65℃; Inert atmosphere;60.2%
With potassium hydroxide In isopropyl alcohol for 4h; Heating;53%
With potassium carbonate In acetonitrile at 50℃; for 20h;
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

74-88-4

methyl iodide

22246-17-9

7-methoxy-2-oxo-1,2,3,4-tetrahydroquinoline

Conditions
ConditionsYield
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With potassium carbonate In isopropyl alcohol at 20℃; for 0.5h; Inert atmosphere;
Stage #2: methyl iodide In isopropyl alcohol for 60h; Reflux;
90%
In N,N-dimethyl-formamide at 20℃;82%
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 18h;63%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

109-64-8

1,3-dibromo-propane

82657-32-7

7-(3-bromopropoxy)-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With potassium carbonate In water; acetone at 20℃; for 1h;
Stage #2: 1,3-dibromo-propane In water; acetone at 20℃; for 16h;
90%
With potassium carbonate In ethanol Reflux;88%
With potassium carbonate In acetonitrile at 60 - 65℃; Inert atmosphere;65.3%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

1092366-87-4

t-butyl 4-(2-nitrophenylsulfonyloxy)piperidine-1-carboxylate

583031-07-6

tert-butyl 4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]piperidine-1-carboxylate

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide at 50℃; for 7h; Williamson Synthesis;87%
With triethylamine In dichloromethane
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

1194459-28-3

6-bromo-7-hydroxy-3,4-dihydro-1H-quinolin-2-one

Conditions
ConditionsYield
With N-Bromosuccinimide In N,N-dimethyl-formamide at 0℃; for 9h;87%
With N-Bromosuccinimide58%
With N-Bromosuccinimide In N,N-dimethyl-formamide at 0 - 20℃;0.82 g
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

358-23-6

trifluoromethylsulfonic anhydride

882023-50-9

2-oxo-1,2,3,4-tetrahydroquinolin-7-yl trifluoromethanesulfonate

Conditions
ConditionsYield
With pyridine In dichloromethane at 10 - 30℃; for 3h;85%
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With pyridine In chloroform at 20℃; for 0.166667h;
Stage #2: trifluoromethylsulfonic anhydride In chloroform at 20℃; for 1.5h; Cooling with ice;
67%
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With pyridine In chloroform at 0 - 40℃; for 0.166667h;
Stage #2: trifluoromethylsulfonic anhydride In chloroform at 10 - 15℃; for 1.58333h;
With pyridine In chloroform at 0 - 23℃; for 18h; Inert atmosphere; Schlenk technique;
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

70-11-1

α-bromoacetophenone

3,4-dihydro-7-(2-oxo-2-phenylethoxy)quinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h; deprotonation;
Stage #2: α-bromoacetophenone In N,N-dimethyl-formamide at 20℃; for 24h; Alkylation;
84%
With potassium carbonate
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

100-39-0

benzyl bromide

92962-89-5

7-(benzyloxy)-3,4-dihydro-2(1H)-quinolinone

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 16h;84%
With potassium carbonate In acetonitrile Heating;79%
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 16h;67%
With potassium hydroxide In ethanol for 5h; Reflux;57%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

89043-32-3

(4-bromobutoxy)-tert-butyldimethylsilane

7-(4-((tert-butyldimethylsilyl)oxy)butoxy)-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
With potassium carbonate In ethanol Reflux;84%
With potassium carbonate; potassium iodide Reflux;84%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

135-73-9

2-Bromo-4'-phenylacetophenone

7-[2-(1,1'-biphenyl-4-yl)-2-oxoethoxy]-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
Stage #1: 7-hydroxy-3,4-dihydro-2-(1H)-quinolinone With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.5h; deprotonation;
Stage #2: 2-Bromo-4'-phenylacetophenone In N,N-dimethyl-formamide at 20℃; for 24h; Alkylation;
80%
With potassium carbonate
6940-78-9

4-chlorobutyl bromide

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

A

7-(4-(2-oxo-1,2,3,4-tetrahydroquinolin-7-oxy)butoxy)-3,4-dihydroquinoline-2(1H)-one

B

120004-79-7

7-(4-chlorobutoxy)-3,4-dihydroquinoline-2(1H)-one

Conditions
ConditionsYield
With sodium hydroxide In ISOPROPYLAMIDE at 36 - 40℃; for 4h; Product distribution / selectivity;A 0.3%
B 80%
22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

88-10-8

N,N-diethylcarbamyl chloride

2-oxo-1,2,3,4-tetrahydroquinolin-7-yl diethylcarbamate

Conditions
ConditionsYield
With pyridine for 12h; Reflux;80%
622-40-2

2-(morpholin-4-yl)ethanol

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

1609210-11-8

7-(2-morpholinoethoxy)-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
With cyanomethylenetributyl-phosphorane In toluene at 100℃; for 16h; Mitsunobu Displacement;80%
5464-12-0

2-(4-methylpiperazinyl)ethanol

22246-18-0

7-hydroxy-3,4-dihydro-2-(1H)-quinolinone

7-[2-(4-methylpiperazin-1-yl)ethoxy]-3,4-dihydroquinolin-2(1H)-one

Conditions
ConditionsYield
With cyanomethylenetributyl-phosphorane In toluene at 100℃; for 16h; Mitsunobu Displacement;80%
  • Display:default sort

    New supplier

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Manufacturer/High quality/Best price/In stock

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Manufacturer/High quality/Best price/In stock

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 3.0-3.0/Kilogram

    DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

    Dayang Chem (Hangzhou) Co.,Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredi

  •  Dayang Chem (Hangzhou) Co.,Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-571-88938639

    Address:9/F, Unit 2 Changdi Torch Building, 259# WenSan Road, Xihu District, Hangzhou City 310012, P.R.China

       Inquiry Now

  • 3,4-Dihydro-7-Hydroxy Carbostyril

  • Casno:

    22246-18-0

    3,4-Dihydro-7-Hydroxy Carbostyril

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Product name :3,4-Dihydro-7-Hydroxy Carbostyril CAS:22246-18-0 We are also manufacturing and supplying below aripiprazole intermediates: Appearance:white powder Storage:keep from moisture,sealed in container contai

    Hangzhou Maytime Bio-Tech Co.,Ltd. specialize in R&D, manufacturing and selling kinds of pharmaceutical raw material, veterinary products, pharmaceutical intermediates. Our techni

  •  Hangzhou Maytime Bio-Tech Co.,Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+86-571-88925295 88920965

    Address:No.1-2-801 Nanan Mingzhu Xiaoshan Economical and Technological Development Zone,Hangzhou ,Zhejiang,China

       Inquiry Now

  • 7-hydroxy-3,4-dihydrocarbostyril

  • Casno:

    22246-18-0

    7-hydroxy-3,4-dihydrocarbostyril

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Hangzhou Fortune Biopharm Co.,Ltd.is a private-owned company which is initially dedicated to R&D of Active pharmaceutical ingredients and intermediates. Our main products include: Acetazolamide,Aminocaproic Acid,Aripiprazole,Butaphospha

    Hangzhou Fortune Biopharm Co.,Ltd.is a private-owned company which is dedicated to R&D and production for Biopharmaceuticals.It was initially established as per requirements of som

  •  Hangzhou Fortune Biopharm Co.,LTD.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-87621708

    Address:279 Zixuan Road,Xihu District,Hangzhou,Zhejiang(310030),China.

       Inquiry Now

  • High quality 3,4-Dihydro-7-Hydroxy-2(1H)-Quinolinone supplier in China

  • Casno:

    22246-18-0

    High quality 3,4-Dihydro-7-Hydroxy-2(1H)-Quinolinone supplier in China

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

    Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional

  •  Simagchem Corporation

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-592-2680277

    Address:21/F Hualong Office Building,No.6 Hubin East Road, Xiamen,China

       Inquiry Now

  • CAS:22246-18-0 7-Hydroxy carbostyril

  • Casno:

    22246-18-0

    CAS:22246-18-0 7-Hydroxy carbostyril

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Item Specification Product Name 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone CAS No. 22246-18-0 Appearance White

    Kono Chem Co.,Ltd is a leading producer of standardized herbal extracts, natural active ingredients and APIs for pharmaceutical, health food and cosmetic industries. Annually, mo

  •  Kono Chem Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-29-86107037-8015

    Address:No.11 Daqing Road,Lianhu District,Xi’an 710082,China

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Min.Order: 5 Metric Ton

    FOB Price:  USD $ 1100.0-1500.0/Metric Ton

    chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res

    Hebei yanxi chemical co. LTD. has expanded a compositive entity from initially only as a small manufacturer. The company dedicated to the development, production and marketing of

  •  Hebei yanxi chemical co.,LTD.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-0311-66561638

    Address:Zhang zhe, guangzong county, xingtai city, hebei province

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    high quality Appearance:White or off white powder Storage:Sealed, dry, microtherm , avoid light and smell Package:According to the demand of customer Application:Pharmaceutical intermediates Transportation:by air or by sea Port:shanghai

    Located in Zhengdong New District,?Zhengzhou of Henan province, Henan Allgreen Chemical Co.,Ltd is a comprehensive high-tech modern enterprises integrating professional R&D, pro

  •  Henan Allgreen Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:+86-0371-87507775

    Address:No 260 Dongming Road,Jinshui District

       Inquiry Now

  • 7-hydroxy-3,4-dihydro-1H-quinolin-2-one

  • Casno:

    22246-18-0

    7-hydroxy-3,4-dihydro-1H-quinolin-2-one

    Min.Order: 10 Milligram

    FOB Price:  USD $ 0.0-0.0/Milligram

    1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

    Founded in 2011, Amadis Chemical Company Limited is an innovative manufacturer of chemical products and technical service providers. Our business includes sales, manufacture, and s

  •  Amadis Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-571-89925085

    Address:Watts Cosine.No.166.Xiangmao Road.

       Inquiry Now

  • 7-Hydroxy-3,4-dihydrocarbostyril

  • Casno:

    22246-18-0

    7-Hydroxy-3,4-dihydrocarbostyril

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Chemwill Asia co.,Ltd is one of the leading manufacturer in CHINA.Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Active pharmaceutical ingredients(APIs), Veterinary, Indole derivatives, Aro

    Our main production base is located in Xuzhou industry park. We produce a wide range of organics including Fine chemicals, Active pharmaceutical ingredients(APIs), Veterinary, In

  •  Chemwill Asia Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:021-51086038

    Address:High-Tech Industrial park,Chemical Economical Development Zone,Xuzhou, Jiangsu-Province, P.R.China

       Inquiry Now

  • 7-Hydroxyquinolinone

  • Casno:

    22246-18-0

    7-Hydroxyquinolinone

    Min.Order: 5 Metric Ton

    FOB Price:  USD $ 1.0-2.0/Metric Ton

    Alias: 7-Hydroxy-2-(1H)-quinolinone; 7-Hydroxycarbostyril; CAS RN: 22246-18-0 Molecular formula: C9H9NO2 Molecular weight: 163.1733 Structural formula: Appearance:Pale white crystalline powder Storage:Store in cool and dry place, away from sun

    Welcome to Henan Sinotech! Sinotech Corporation has exceptional sourcing ability for chemicals used in Organic Fine Chemicals and APIs; Inorganic chemicals; Flame Retardants;OLED

  •  Henan Sinotech Import&Export Corporation

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-371-86181678

    Address:No. 260, Dongming Road,Jinshui District

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Min.Order: 1 Gram

    FOB Price:  USD $ 45.0-45.0/Gram

    Product Description Product website: http://www.finerchem.com Product Name 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Jinan Finer Chemical Co., Ltd is established under the support of Jinan city government, so it has many advantages in company credibility, finance safe, product quality control and

  •  Jinan Finer Chemical Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-531-88989536

    Address:New Material Industry Park, Jinan Ciyt, China

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Basic information Product Name: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Synonyms: AURORA KA-4813;(1H)-7-HYDROXY-3,4-DIHYDRO-2-QUINOLINONE;7-HYDROX

    Our company engages in Electronic chemicals such as OLED,Photoresist chemical,Electrolyte additive and Intermediate Pharmaceutical production; development of noble metal catalysts,

  •  Henan Tianfu Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-371-55170693/55170694

    Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone  CAS 22246-18-0

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone CAS 22246-18-0

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white crystalline powder Storage:Store in sealed containers

    Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s)

  •  Hubei XinRunde Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+8618874586545

    Address:No.43, Xinandu Industrial Park, East and West Lake District, Wuhan, Hubei, China

       Inquiry Now

  • 7-hydroxy-3,4-dihydro-1H-quinolin-2-one

  • Casno:

    22246-18-0

    MSDS/COA Download

    7-hydroxy-3,4-dihydro-1H-quinolin-2-one

    Min.Order: 100 Gram

    FOB Price:  USD $ 1.0-1.0/Gram

    Superiority 1, High quality with competitive price: 1)Purity≥ 99% 2)We are manufacturer and can provide high quality products with factory price,offering free samples to test, a few shipping fee only. 2.Fl

    We are Hebei miaobian Biotechnology Co., Ltd , mainly deal in pharmaceutical intermediates and various chemicals. It is with a registered capital of 3 million yuan, is one of the m

  •  Hebei miaobian Biotechnology Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:17633233896

    Address:Federal Business Plaza, Qiaoxi District,Shijiazhuang

       Inquiry Now

  • New production CAS 22246-18-0 with best quality

  • Casno:

    22246-18-0

    New production CAS 22246-18-0 with best quality

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 139.0-210.0/Kilogram

    WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

    Zhuo Zhou Wen Xi Import and Export Co., Ltd. is a company mainly engaged in the export of pharmaceutical raw materials. Its parent company is (Wen Xi Pharma), including three subs

  •  Zhuozhou Wenxi import and Export Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-13111626072

    Address:Room 1710, Baoxin International Phase I, 19 Guanyun East Road, Zhuozhou, Hebei

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone/ LIDE PHARMA- Factory supply / Best price

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone/ LIDE PHARMA- Factory supply / Best price

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&

    LIDE PHARMACEUTICALS LIMITED is one of the fastest growing pharmaceutical company in China. We have developed strategic partnership with our manufacturing associates having state o

  •  LIDE PHARMACEUTICALS LIMITED

    China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-25-58409506

    Address:11F, Building A1, No.288 North Zhongshan Road, Gulou District, Nanjing,210003, P.R.China.

       Inquiry Now

  • 22246-18-0 7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE

  • Casno:

    22246-18-0

    MSDS/COA Download

    22246-18-0 7-HYDROXY-3,4-DIHYDRO-2(1H)-QUINOLINONE

    Min.Order: 10 Gram

    FOB Price:  USD $ 2.0-2.0/Gram

    superiority advantages: my company is a renowned pharmaceutical manufacturer. we can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. never stop striving to offer our best service is our philoso

    HUBEI AOKS BIO-TECH CO.,LTD is located in Hubei province of China.We specialized in Active pharmaceutical ingredient,pharmaceutical intermediates,veterinary drug intermediates and

  •  HUBEI AOKS BIO-TECH CO.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-27-52345788

    Address:28F,China Construction Third Bureau,Wuhan,Hubei Province, China

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone  CAS 22246-18-0

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone CAS 22246-18-0

    Min.Order: 10 Gram

    FOB Price:  USD $ 1.0-2.0/Gram

    1,Best Quality: Our products have exported to Germany, Spain, UK, USA, Australia, Middle East, and so on other countries, and we have got very good feedback from our customers.so

    Hubei Jusheng Technology Co., Ltd., is a large group corporation which engaged in the R&D and manufacture of chemicals, Pharmaceuticals and intermediates. We have earned ourselves

  •  Hubei Jusheng Technology Co., Ltd.,

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-18871490254

    Address:High-tech Industrial Park,Tianmen city,Hubei province.

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone 22246-18-0

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone 22246-18-0

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

    Shanghai Upbio Tech Co.,Ltd (Former Onchem (China)Co.,Ltd) is a comprehensive manufacturer and an international distribution of chemicals throughout the world, The predecessor of

  •  Shanghai Upbio Tech Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-21-52196435

    Address:No.2 Floor,No.979 Yunhan Rd,Nicheng,Pudong New Area,Shanghai,China

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone CAS NO.22246-18-0

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone CAS NO.22246-18-0

    Min.Order: 10 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

    Changchun Artel Import and Export Trade Co., Ltd. is located in Changchun City, Jilin Province. It is a high-tech modern private enterprise specializing in the research, developme

  •  Changchun Artel lmport and Export trade company

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-0431-80543058

    Address:Dianshi Plazza,Chaoyang District

       Inquiry Now

  • CAS NO.22246-18-0 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

  • Casno:

    22246-18-0

    MSDS/COA Download

    CAS NO.22246-18-0 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Min.Order: 1 Gram

    FOB Price:  USD $ 50.0-100.0/Gram

    CAS NO.22246-18-0 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Superiority Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) W

    Wuhan Monad Medicine Tech Co.,LTD is a research and development, production, sales in one high-tech company, own about 100 kinds of products, can provide about more than 30000 kind

  •  Wuhan Monad Medicine Tech Co.,LTD

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8615871419939

    Address:13th Floor, Tower B, Century Plaza, Zhongnan Road, Wuchang District, Wuhan, China.

       Inquiry Now

  • Factory Direct Sales Low Price 99% 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

  • Casno:

    22246-18-0

    Factory Direct Sales Low Price 99% 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Long-term export and transportation experience, 100% processing your order!Fast and safe delivery!Packing: 1kg, 25kg..or base on your inquiy.Our advantages:Long-term export experience allows you to receive goods quickly and safely.1, High quality wit

    Shaanxi Mingqi Chemical Co., Ltd is committed to the development of import and export trade in the production, operation and plant extracts of pharmaceutical raw materials and inte

  •  Shaanxi Mingqi Chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:18092428356

    Address:Weiyang District

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone CAS 22246-18-0

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone CAS 22246-18-0

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 10.0-10.0/Kilogram

    Our advantages: 1, high quality with competitive price: 1) standard:bp/usp/ep/enterprise standard 2) all purity≥99% 3) we are manufacturer and can provide high quality products with factory price. 2, fast and safe delivery

    Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group,which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector amon

  •  Hebei Guanlang Biotechnology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+8619930503256

    Address:No.66, Yuhua West Road

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

    Shandong Hanjiang Chemical Co., Ltd. is located in Qilu Petrochemical Industrial Park, Zibo City, Shandong Province, involving pesticide, medicine, chemical industry, coating, dy

  •  Shandong Hanjiang Chemical Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:18369939125

    Address:95A, Xingyuan East Road, Zhangdian District

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Manufactory best quality

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Manufactory best quality

    Min.Order: 100 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Product Name: 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone Synonyms: Aripiprazole Impurity 21(Aripiprazole EP Impurity A);4-Dihydro-7-hydroxy-2(1H)-quinolinone;Aripiprazole EP Impurity A;Aripiprazole intermediate;22246-18-0;7-Hydroxy-3,4-dihydro-2(1H

    Wuhan Zenuo Biopharmaceutical Technology Co., Ltd. is a global biopharmaceutical and chemical enterprise, mainly engaged in the customized synthesis, large-scale production and sal

  •  Wuhan Zenuo Biological Medicine Technology Co Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:(+86-27)8700-2750

    Address:Floor 19th,No.76,Longyang Road

       Inquiry Now

  • 7-hydroxy-3,4-dihydro-1H-quinolin-2-one  Aripiprazole CAS NO.22246-18-0

  • Casno:

    22246-18-0

    7-hydroxy-3,4-dihydro-1H-quinolin-2-one Aripiprazole CAS NO.22246-18-0

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1.0-9999.0/Kilogram

    Changzhou Pesan Chemical Co., Ltd. is a dynamic and professional chemical company. Since its establishment, We provide raw materials and intermediates for the pharmaceutical industry and organic electronic materials. All of our staff have a chem

    Changzhou Pesan Chemical Co., Ltd. is a dynamic and specialized chemical company. Since our establishment, We provide raw materials and key intermediates for pharmaceutical industr

  •  Changzhou Pesan Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:+86 021 61559630

    Address:No.7-9,Guanghua St.,Zhonglou District,Changzhou,China

       Inquiry Now

  • 7-Hydroxy-3,4-Dihydro-2(1H)Quinolinone

  • Casno:

    22246-18-0

    7-Hydroxy-3,4-Dihydro-2(1H)Quinolinone

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0/

    Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

    Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, special chemicals and OLED materials &

  •  Xiamen Hisunny Chemical Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Manufacturers

    Tel:86-592-3327115

    Address:Unit 603,No.879,Xiahe Road,Meixin Building,Xiamen,China

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Shanghai, Run-Biotech Co., Ltd is a leading domestic pharmaceutical, biopharmaceutical, and health care products R & D outsourcing services company. As an innovation-driven and customer-focused company, Run Biotech provides a broad and integrat

    Dine products include organic reagents, inorganic reagents and biochemical reagents, including pharmaceutical intermediates, bulk drugs, catalysts, high purity solvents, specialty

  •  Shanghai Run-Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-21-57171705 / 57171706

    Address:No.787, Kangqiao Road, Pudong New District, Shanghai, China

       Inquiry Now

  • 7-Hydroxyquinolinone/factory price directly

  • Casno:

    22246-18-0

    MSDS/COA Download

    7-Hydroxyquinolinone/factory price directly

    Min.Order: 10 Kilogram

    FOB Price:  USD $ 0.0-0.0/Kilogram

    Superiority Best price,best quality and fast delivery assurance Available in sample product and customization With years of export experience along with excellent quality, advanced services and competitive prices The quali

    We, Jilin Tely Imp & Exp Co., Ltd. mainly supply and export products including: pharmaceutical raw materials,Chemical reagents, Food additives, pharmaceutical and pesticide interme

  •  Jilin Tely Imp.& Exp.Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-431-81915458

    Address:Room 302, 47 Changping Street, Chaoyang District, Changchun, Jilin Province,China

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 1550.0-1600.0/Kilogram

    1.Coreychem focus on high complex new type intermediates and fine chemical custom synthesis,scale-up production and rare chemicals trade.Product category including Intermediates&API,Catalyst and Electronic Chemicals.Covering 811 square meters R

    Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded t

  •  Career Henan Chemical Co

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-371-86658258

    Address:Building 3 of Innovation Park, East District of the National University Science Park

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Min.Order: 1 Gram

    FOB Price:  USD $ 1.0-2.0/Gram

    span lang="EN-US" style="font-size: 9.0pt;font-family:"Arial",sans-serif;color:#4D4D4D">As a leading manufacturer and supplier of chemicals in china, weckchem not only supply popular chemicals, but also weckchem’s r&d center off

    Hangzhou Weckchem Co.,Ltd, located in Hangzhou,China, is specialized in Green chemicals and Fine chemicals over 10 years. Our main products are used in Fuel oil, Water treatment an

  •  Hangzhou Weck Chemical Industry Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Other

    Tel:86-15158040660

    Address:Xiaoshan district

       Inquiry Now

  • 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

  • Casno:

    22246-18-0

    3,4-Dihydro-7-hydroxy-2(1H)-quinolinone

    Min.Order: 1 Gram

    FOB Price:  USD $ 0.0-0.0/Gram

    Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

    Shanghai BetterBioChem Co., Ltd. specializes in research, production of APIs, building blocks and key pharmaceutical intermediates. We provide our products from milligrams to kilog

  •  Shanghai BetterBioChem Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-18013506594

    Address:No. 8 Building, 18 nong, Xi Yingnan Road, Pudong, Shanghai,China

       Inquiry Now

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Chemistry

Molecular Structure of 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone (CAS NO.22246-18-0):

IUPAC Name: 7-hydroxy-3,4-dihydro-1H-quinolin-2-one
Molecular formula: C9H9NO2
Molar weight: 163.17
H bond acceptors: 3
H bond donors: 2
Freely Rotating Bonds: 1
Polar Surface Area: 29.54 Å2
Index of Refraction: 1.604
Molar Refractivity: 43.78 cm3
Molar Volume: 127.2 cm3
Surface Tension: 51.7 dyne/cm
Density: 1.282 g/cm3
Flash Point: 198 °C
Enthalpy of Vaporization: 68.06 kJ/mol
Boiling Point: 403.7 °C at 760 mmHg
Vapour Pressure: 4.28E-07 mmHg at 25°C
Melting point: 233-237 °C
Appearance: Pale Yellow Powder
Product Categories: Quinolines, Quinazolines and derivatives; Quinoline derivatives; Intermediatesofaripiprazole; Aromatics Compounds; Intermediates of Aripiprazole; Aromatics; Intermediates & Fine Chemicals; Pharmaceuticals
SMILES: O=C2Nc1cc(O)ccc1CC2
InChI: InChI=1/C9H9NO2/c11-7-3-1-6-2-4-9(12)10-8(6)5-7/h1,3,5,11H,2,4H2,(H,10,12)

Safety Profile

Hazard Codes: HarmfulXn,IrritantXi
The Risk Statements information:
22:  Harmful if swallowed 
43:  May cause sensitization by skin contact 
The Safety Statements information:
36/37:  Wear suitable protective clothing and gloves 

Specification

  3,4-Dihydro-7-hydroxy-2(1H)-quinolinone , with CAS number of 22246-18-0, can be called 3,4-Dihydrogen-7-Hydroxy-2(1H)-Quinolinone ; 7-Hydroxy-3,4-dihydro-2(1H)Quinolineone ; 2(1H)-Quindinone,3,4-dohydro-7Hydroxy ; 7-(4-bromo-butoxy)-3,4-dihydro-1H-quinolin-2-one ; 7-Hydroxy-1,2,3,4-tetrahydro-2-quinolinone ; 7-Hydroxy-1,2,3,4-tetrahydroquinoline ; 3,4-dihydro-7-hydroxy quinolin-2(1H)-one . It is a pale yellow powder.