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246869-08-9

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Basic Information
CAS No.: 246869-08-9
Name: 2-(cyclopropylmethoxy)acetic acid
Article Data: 5
Molecular Structure:
Molecular Structure of 246869-08-9 (2-(cyclopropylmethoxy)acetic acid)
Formula: C6H10O3
Molecular Weight: 130.144
Synonyms: Acetic acid,(cyclopropylmethoxy);(cyclopropylmethoxy)acetic acid;2-(3-METHOXYPHENYL)ETHANIMIDAMIDE HYDROCHLORIDE;2-(Cyclopropylmethoxy)-acetic Acid;
Density: 1.201±0.06 g/cm3(Predicted)
Boiling Point: 267.1±13.0 °C(Predicted)
PSA: 46.53000
LogP: 0.49760
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Synthetic route
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Conditions
ConditionsYield
With potassium tert-butylate In tetrahydrofuran at -5 - 5℃; for 18h; Temperature; Solvent;90%
2516-33-8

Cyclopropylmethanol

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sodium monochloroacetic acid

246869-08-9

2-(cyclopropylmethoxy)acetic acid

Conditions
ConditionsYield
With sodium hydride In tetrahydrofuran
Stage #1: Cyclopropylmethanol With sodium hydride In tetrahydrofuran for 3h; Reflux;
Stage #2: sodium monochloroacetic acid In tetrahydrofuran for 8.5h;		1.59 g
Stage #1: Cyclopropylmethanol With potassium tert-butylate In tetrahydrofuran at 50℃; for 1h; Inert atmosphere;
Stage #2: sodium monochloroacetic acid In tetrahydrofuran at 20 - 40℃; for 40.5h;		8.08 g
Williamson Ether Synthesis;

2-bromo-2-methyl-1-(4-(methylsulfonyl)phenyl-[13C6])propan-1-one

246869-08-9

2-(cyclopropylmethoxy)acetic acid

2-methyl-1-(4-(methylsulfonyl)phenyl-[13C6])-1-oxopropan-2-yl 2-(cyclopropylmethoxy)acetate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In ethanol for 14h; Heating;97%
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2-(cyclopropylmethoxy)acetic acid

189955-79-1

2-bromo-2-methyl-1-[4-(methylsulfonyl)phenyl]propan-1-one

246869-15-8

2-cyclopropylmethoxyacetic acid [1,1-dimethyl-2-(4-methanesulfonylphenyl)-2-oxoethyl]ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In ethanol at -10 - 20℃;83%
With N-ethyl-N,N-diisopropylamine In methanol at 0℃; for 7h; Reflux;52%
246869-08-9

2-(cyclopropylmethoxy)acetic acid

180048-73-1

2-hydroxy-2-methyl-1-(4-(methylsulfonyl)-phenyl)propan-1-one

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2-cyclopropylmethoxyacetic acid [1,1-dimethyl-2-(4-methanesulfonylphenyl)-2-oxoethyl]ester

Conditions
ConditionsYield
With dmap In dichloromethane
Stage #1: 2-(cyclopropylmethoxy)acetic acid With thionyl chloride; N,N-dimethyl-formamide In dichloromethane at 0 - 20℃; for 6h;
Stage #2: 2-hydroxy-2-methyl-1-(4-(methylsulfonyl)-phenyl)propan-1-one With dmap; triethylamine In dichloromethane at 20℃; for 8h;		6.1 g
246869-08-9

2-(cyclopropylmethoxy)acetic acid

3-(Cyclopropylmethoxy)-5.5-dimethyl-4-(4-(methylsulfonyl)phenyl)-5H-furan-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: CMC, DMAP / CH2Cl2
2: DBU / acetonitrile
View Scheme
Multi-step reaction with 4 steps
1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 10 - 35 °C
2: triethylamine / dichloromethane / 0 - 20 °C
3: 1,8-diazabicyclo[5.4.0]undec-7-ene; isopropyl Trifluoroacetate / toluene / 100 °C
4: copper(l) iodide; (2S,4R)-N-(2,6-dimethylphenyl)-4-hydroxypyrrolidine-2-carboxamide; potassium phosphate / dimethyl sulfoxide / 24 h / 90 °C / Inert atmosphere
View Scheme
246869-08-9

2-(cyclopropylmethoxy)acetic acid

2-(cyclopropylmethoxy)acetyl chloride

Conditions
ConditionsYield
With thionyl chloride; N,N-dimethyl-formamide In dichloromethane at 10 - 35℃;
246869-08-9

2-(cyclopropylmethoxy)acetic acid

C16H19BrO4

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 10 - 35 °C
2: triethylamine / dichloromethane / 0 - 20 °C
View Scheme
246869-08-9

2-(cyclopropylmethoxy)acetic acid

4-(4-bromophenyl)-3-(cyclopropylmethoxy)-5,5-dimethylfuran-2(5H)-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 10 - 35 °C
2: triethylamine / dichloromethane / 0 - 20 °C
3: 1,8-diazabicyclo[5.4.0]undec-7-ene; isopropyl Trifluoroacetate / toluene / 100 °C
View Scheme
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    Tel:+86-18871490254

    Address:High-tech Industrial Park,Tianmen city,Hubei province.

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  • 2-(Cyclopropylmethoxy)-acetic Acid

  • Casno:

    246869-08-9

    2-(Cyclopropylmethoxy)-acetic Acid

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the 2-(Cyclopropylmethoxy)-acetic Acid, CAS:246869-08-9 with the most competitive price a

    Finetech Industry Limited is a company in England,which specializing in developing, manufacturing and marketing fine organic compounds and intermediates for the fine chemical and p

  • Finetech Industry Limited

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-27-87465837

    Address:wuhan

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  • 2-(cyclopropylmethoxy)Acetic acid

  • Casno:

    246869-08-9

    2-(cyclopropylmethoxy)Acetic acid

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    2-(cyclopropylmethoxy)Acetic acidAppearance:white crystalline powder Storage:Shading, sealed, dry place. Package:aluminous bag Application:API Transportation:SEA OR AIR

    Locating in Changchun bonded area, which has absolute advantage of importing and exporting, with the R&D team having more than 10 years experience of OLED material and intermediate

  • changchun tuocai technology co.,ltld

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-431-81292405

    Address:no.7299,airport road

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  • 2-(cyclopropylmethoxy)Acetic acid

  • Casno:

    246869-08-9

    2-(cyclopropylmethoxy)Acetic acid

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

    Our company has been engaged in the Pharmaceutical raw material and pharmaceutical intermediates medicine material intermediates and related chemical industry for more than ten ye

  • Taizhou volsen chemical Co., Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+86-576-88869393

    Address:Jiaojiang District, Taizhou, Zhejiang, China.

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  • 246869-08-9

  • Casno:

    246869-08-9

    246869-08-9

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    2-(cyclopropylmethoxy)Acetic acid Application:API

    We are Hebei minshang biotechnology co. LTD., mainly deal in pharmaceutical intermediates and various chemicals. We are manufacturers and have our own factory. Products & Usage Ph

  • Hebei Minshang Biotechnology Co., Ltd

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:18032092709

    Address:hebei

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  • Acetic acid, (cyclopropylmethoxy)-

  • Casno:

    246869-08-9

    Acetic acid, (cyclopropylmethoxy)-

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Acetic acid, (cyclopropylmethoxy)- Storage:Store in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/Pharmaceutical intermediates Transportation:By Sea,by Air,By courier like DHL or Fedx. Port:Shangha

    Nanjing Raymon Biotech Co., Ltd. is specialized in developing and marketing middle & high level pharmaceutical intermediates. We are supplying different categories of high-quality

  • Nanjing Raymon Biotech Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:86-025-52181296

    Address:Block B, No. 918, Shuanglong Avenue

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  • 2-(cyclopropylmethoxy)Acetic acid

  • Casno:

    246869-08-9

    2-(cyclopropylmethoxy)Acetic acid

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    2-(cyclopropylmethoxy)Acetic acidAppearance:white crystalline powder Storage:Shading, sealed, dry place. Package:aluminous bag Application:API Transportation:SEA OR AIR

    Shanghai PengMo Biotechnology Co., Ltd. is engaging in researching, developing, manufacturing and exporting advanced pharmaceutical intermediates and other fine chemicals. Our comp

  • Shanghai PengMo Biotechnology Co.,Ltd

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:86-13052359378

    Address:No.218 Hai Qu Road.Shanghai.China

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  • 2-(cyclopropylmethoxy)Acetic acid

  • Casno:

    246869-08-9

    2-(cyclopropylmethoxy)Acetic acid

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    2-(cyclopropylmethoxy)Acetic acid Application:2-(cyclopropylmethoxy)Acetic acid

    Hangzhou Fenjunchem Co.,Ltd dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s); Nutr

  • Hangzhou Fenjun Chemical Co Ltd.

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-0571-56263321

    Address:hangzhou

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  • 246869-08-9

  • Casno:

    246869-08-9

    246869-08-9

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Supply top quality products with a reasonable price Application:api

    Hebei Ruishun Trade Co.,Ltd registered capital one million, we have a production of pharmaceutical raw materials, pharmaceutical raw materials factory reagent r&d center, we do

  • Hebei Ruishun Trade Co.,Ltd

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86-311-68037669

    Address:WanDa commerce building ,yuhua district

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  • 2-(cyclopropylmethoxy)Acetic acid

  • Casno:

    246869-08-9

    2-(cyclopropylmethoxy)Acetic acid

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four yearsOur key scientific leadership team has gained experience in top research and developmen

    Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four years Our key scienti

  • Debye Scientific

     China (Mainland)  |  Contact Details

    Business Type:Lab/Research institutions

    Tel:+85221376140

    Address:Rm. 19C, Lockhart Ctr., 301-307 Lockhart Rd., Wan Chai

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  • Acetic acid, (cyclopropylmethoxy)-

  • Casno:

    246869-08-9

    Acetic acid, (cyclopropylmethoxy)-

    Min.Order: 0

    FOB Price:  USD $ 0.0-0.0

    Manufacturer,strong R&D,professional team Storage:Store in a cool, dry place. Store in a tightly closed container. Package:according to your requirement Application:ZhiShang Chemical is owned by ZhiShang Group, is a professional new-type chemicals en

  • Chemical Co.Ltd

    China (Mainland)  |  Contact Details

    Business Type:Trading Company

       Inquiry Now

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