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| CAS No.: | 298-93-1 |
|---|---|
| Name: | Thiazolyl Blue |
| Molecular Structure: | |
|
|
|
| Formula: | C18H16BrN5S |
| Molecular Weight: | 414.329 |
| Synonyms: | 2H-Tetrazolium,2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-, bromide (8CI,9CI);3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazoliumbromide (6CI,7CI);(3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide);2,5-Diphenyl-3-(4,5-dimethylthiazol-2-yl)-2H-tetrazolium bromide;2-(4,5-Dimethylthiazol-2-yl)-3,5-diphenyl-2H-tetrazolium bromide;3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyltetrazolium bromide;3-(4,5-Dimethylthiazolyl)-2,5-diphenyltetrazolium bromide;MMTTetrazolium;MTT;MTT tetrazolium;NSC 60102;Thiazolyl blue (Sigma);Thiazolyl blue tetrazolium bromide; |
| EINECS: | 206-069-5 |
| Density: | 1.4886 (estimate) |
| Melting Point: | 195 °C (dec.)(lit.) |
| Solubility: | slightly soluble in water |
| Appearance: | yellow crystalline powder |
| Hazard Symbols: |
 Xi,  T
|
| Risk Codes: | 46 |
| Safety: | 22-24/25-53-45 |
| PSA: | 75.72000 |
| LogP: | 0.28830 |
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- 298-93-1
thiazolyl blue
| Conditions | Yield |
|---|---|
| With N-Bromosuccinimide; ethyl acetate |
| Conditions | Yield |
|---|---|
| In water mixing of aq. solns. of Na2MoO4*2H2O, 4-nitrocatechol and 3-(4,5-dimethylthiaozol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide in acidic medium (pH2.8 - 4.0); pptn., filtration, washing with cold water, drying at 75-80°C; |
- 298-93-1
thiazolyl blue
- 23305-68-2
1-(4,5-dimethyl-2-thiazoyl)-3,5-diphenylformazan
| Conditions | Yield |
|---|---|
| With dehydrogenase | |
| With succinate dehydrogenase at 37℃; for 4h; |
| Conditions | Yield |
|---|---|
| With sulfuric acid In water |
- 298-93-1
thiazolyl blue
- 37422-56-3
5-methyl-4-(2-thiazolylazo)resorcinol
| Conditions | Yield |
|---|---|
| In chloroform; water |
- 298-93-1
thiazolyl blue
| Conditions | Yield |
|---|---|
| With mitochondrial reductase Enzymatic reaction; |
- 298-93-1
thiazolyl blue
| Conditions | Yield |
|---|---|
| With A549 cells for 1h; Enzymatic reaction; | |
| With mitochondrial dehydrogenase Enzymatic reaction; |
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Chemistry
IUPAC Name: Thiazolyl blue
The MF of Thiazolyl blue (298-93-1) is C18H18BrN5S.
The MW of Thiazolyl blue (298-93-1) is 416.34.
Synonyms of Thiazolyl blue (298-93-1): 3-(4,5-Dimethyl-1,3-thiazol-2-yl)-2,5-diphenyl-2H-tetrazol-3-ium bromide ; 2-(4,5-Dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-2H-tetrazol-3-ium bromide ; 2-(4,5-Dimethyl-2-thiazolyl)-3,5-diphenyl-2H-tetrazolium bromide
Product Categories: Tetrazolium Salts;Tetrazolium Salts & Formazans;Chemistry
Form: yellow crystalline powder
EINECS: 206-069-5
Melting Point: 195 °C
Storage temp: 2-8°C
Solubility in methanol: 5 mg/mL, clear
Sensitive: Light Sensitive
BRN: 3825277
Toxicity Data With Reference
| 1. | mmo-sat 5 µg/plate | MUREAV Mutation Research. 68 (1979),107. | ||
| 2. | mmo-esc 5 µg/plate | MUREAV Mutation Research. 68 (1979),107. |
Safety Profile
Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also BROMIDES.
Safety information of Thiazolyl blue (298-93-1):
Hazard Codes .gif){kind=small}
Xi,.gif){kind=small}
T
Risk Statements
46 May cause heritable genetic damage
Safety Statements
22 Do not breathe dust
24/25 Avoid contact with skin and eyes
53 Avoid exposure - obtain special instruction before use
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
WGK Germany 3
RTECS XF8060000
F 3-8-10
HS Code 29341000