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CAS No.: | 3482-14-2 |
---|---|
Name: | 8-Isoquinolinol |
Article Data: | 8 |
Molecular Structure: | |
Formula: | C9H7NO |
Molecular Weight: | 145.161 |
Synonyms: | 8-Hydroxyisoquinoline;NSC 400234;Isoquinolin-8-ol; |
EINECS: | -0 |
Density: | 1.26 g/cm3 |
Melting Point: | 213 °C |
Boiling Point: | 332.074 °C at 760 mmHg |
Flash Point: | 154.633 °C |
Appearance: | white solid |
Hazard Symbols: | Xi |
Risk Codes: | 22 |
PSA: | 33.12000 |
LogP: | 1.94040 |
Conditions | Yield |
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Stage #1: 8-methoxyisoquinoline With boron tribromide In dichloromethane at 0 - 20℃; for 2.5h; Heating / reflux; Stage #2: With methanol at -78 - 20℃; for 0.5h; Heating / reflux; | 98% |
With boron tribromide In dichloromethane for 1h; demethylation; Heating; | 83% |
8-chloroisoquinoline
isoquinolin-8-ol
Conditions | Yield |
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With copper acetylacetonate; lithium hydroxide monohydrate; 1,3-bis(4-hydroxy-2,6-dimethylphenyl)urea In water; dimethyl sulfoxide at 130℃; for 24h; Inert atmosphere; | 72% |
Conditions | Yield |
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biotransformation by Pseudomonas putida UV4; | A 5 mg B 43 mg C 41 mg |
isoquinolin-8-ol
Conditions | Yield |
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With sulfuric acid; sulfur trioxide at 300℃; Erhitzen des Reaktionsprodukts mit Natriumhydroxid unter Zusatz von Wasser auf 210grad; |
Conditions | Yield |
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Multi-step reaction with 2 steps 1.1: benzene / 5 h / Heating 1.2: ClCO2Et; (MeO)3P / 13 / 72 h / 20 °C 1.3: TiCl4 / 15 / 1 h / Heating 2.1: boron tribromide / dichloromethane / 1 h / Heating View Scheme |
isoquinolin-8-ol
Conditions | Yield |
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With sodiumsulfide nonahydrate In ethanol at 40℃; for 20h; |
isoquinolin-8-ol
Conditions | Yield |
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With bromine; sodium hydrogencarbonate In methanol at 20℃; for 0.0833333h; | 96% |
isoquinolin-8-ol
1,2,3,4-tetrahydro-8-hydroxyisoquinoline acetate
Conditions | Yield |
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With hydrogen; acetic acid; platinum(IV) oxide In ethanol under 3000.3 Torr; for 18h; | 92% |
Conditions | Yield |
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With potassium carbonate; potassium iodide In acetonitrile at 20℃; | 90% |
isoquinolin-8-ol
carbonic acid 1,1-dimethylethyl 1-phenyl-2-propenyl ester
Conditions | Yield |
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With (S)-(+)-N-(3,5-dioxa-4-phosphacyclohepta-[2,1-a;3,4-a′]dinaphthalen-4-yl)dibenz[b,f]azepine; bis(1,5-cyclooctadiene)diiridium(I) dichloride In methanol at 25℃; for 0.1h; Inert atmosphere; enantioselective reaction; | 87% |
Molecular structure of 8-Isoquinolinol (CAS NO.3482-14-2) is:
Product Name: 8-Isoquinolinol
CAS Registry Number: 3482-14-2
IUPAC Name: 2H-isoquinolin-8-one
Molecular Weight: 145.15798 [g/mol]
Molecular Formula: C9H7NO
XLogP3-AA: 1
H-Bond Donor: 1
H-Bond Acceptor: 2
Index of Refraction: 1.691
Molar Refractivity: 44.068 cm3
Molar Volume: 115.203 cm3
Surface Tension: 59.731 dyne/cm
Density: 1.26 g/cm3
Flash Point: 154.633 °C
Enthalpy of Vaporization: 59.761 kJ/mol
Boiling Point: 332.074 °C at 760 mmHg
Product Categories: Isoquinoline;blocks;Heterocycles;Quinolines;Heterocyclic Series;Quinoline&Isoquinoline;Building Blocks
Hazard Codes: Xi
Hazard Note: Irritant
8-Isoquinolinol , its cas register number is 3482-14-2. It also can be called 8-Hydroxyisoquinoline ; Isoquinolin-8-ol ; 8-Isoquinolinol(6CI,7CI,8CI,9CI) ; 2H-isoquinolin-8-one .