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Basic Information
CAS No.: 36946-70-0
Name: 2-Aminoindole hydrochloride
Molecular Structure:
Molecular Structure of 36946-70-0 (2-Aminoindole hydrochloride)
Formula: C8H8 N2
Molecular Weight: 132.165
Synonyms: 2-Aminoindole
Density: 1.268±0.06 g/cm3(Predicted)
Melting Point: 215-220 ºC dec.
Boiling Point: 372.4°C at 760 mmHg
Flash Point: 179°C
PSA: 41.81000
LogP: 3.13330
Synthetic route
1131148-08-7

(1H-indol-1-yl)(pyridin-2-yl)methanone

36946-70-0

indoleamine

Conditions
ConditionsYield
Stage #1: (1H-indol-1-yl)(pyridin-2-yl)methanone With tert.-butylnitrite; copper diacetate In 1,4-dioxane at 70℃; for 16h;
Stage #2: With hydrazine hydrate; FeCl3/C In 1,4-dioxane; ethanol at 70℃;
93%
193686-70-3

2-nitroindole

36946-70-0

indoleamine

Conditions
ConditionsYield
With sodium tetrahydroborate In water at 60℃; for 0.25h; Sonication;88%
610-66-2

2-nitro-benzeneacetonitrile

36946-70-0

indoleamine

Conditions
ConditionsYield
With hydrogenchloride In ethanol at 30℃; for 3h;52%
101258-96-2

2-methyl-2-pyrrolidin-1-yl-propan-1-ol

27667-51-2

5-Hydroxy-2-methyl-1H-indole-3-carboxylic acid benzyl ester

133-59-5

Toluene-2-sulfonyl chloride

A

36946-70-0

indoleamine

B

459449-48-0

2-Methyl-5-(2-methyl-2-pyrrolidin-1-yl-propoxy)-1H-indole-3-carboxylic acid benzyl ester

Conditions
ConditionsYield
With potassium carbonate; triethylamine; trifluoroacetic acid In acetonitrileA n/a
B 5%
2973-50-4

2-aminophenylacetonitrile

141-52-6

sodium ethanolate

hydrogen

hydrogen

36946-70-0

indoleamine

861571-31-5

(2-formylamino-phenyl)-acetonitrile

potassium carbonate

potassium carbonate

36946-70-0

indoleamine

36946-70-0

indoleamine

326-06-7

1-Phenyl-4,4,4-trifluorobutane-1,3-dione

869465-09-8

2-phenyl-4-(trifluoromethyl)-9H-pyrido[2,3-b]indole

Conditions
ConditionsYield
With acetic acid for 1h; Heating;89%
With acetic acid for 2h; Inert atmosphere; Reflux; regiospecific reaction;89%
36946-70-0

indoleamine

356-40-1

sodium 5,5,6,6,6-pentafluoro-2,4-hexanedione

1190370-62-7

2-methyl 4-(perfluoroethyl)-9H-pyrido[2,3-b]indole

Conditions
ConditionsYield
With acetic acid for 2h; Inert atmosphere; Reflux; regiospecific reaction;87%
36946-70-0

indoleamine

1522-22-1

1,1,1,5,5,5-hexafluoroacetylacetone

869465-16-7

2,4-bis(trifluoromethyl)-9H-pyrido[2,3-b]indole

Conditions
ConditionsYield
With acetic acid for 2h; Inert atmosphere; Reflux; regiospecific reaction;86%
36946-70-0

indoleamine

2062-21-7

1-Chlor-1,1-difluor-3-benzoyl-aceton

869465-10-1

4-(chlorodifluoromethyl)-2-phenyl-9H-pyrido[2,3-b]indole

Conditions
ConditionsYield
With acetic acid for 2h; Inert atmosphere; Reflux; regiospecific reaction;85%
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Chemistry

Molecular Structure of 2-Aminoindole hydrochloride (CAS NO.36946-70-0):

Molecular Formula: C8H9ClN2
Molecular Weight: 168.6235 
Systematic Name: 1H-Indol-2-amine hydrochloride (1:1)
Synonyms of 2-Aminoindole hydrochloride (CAS NO.36946-70-0): 1H-Indol-2-amine hcl
CAS NO: 36946-70-0
Product Categories: Nitrogen cyclic compounds ; Indole Derivatives
Melting point: 215-220°C 
Flash Point: 179 °C
Enthalpy of Vaporization: 63.17 kJ/mol
Boiling Point: 372.4 °C at 760 mmHg
Vapour Pressure: 6.6E-06 mmHg at 25°C