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| CAS No.: | 36946-70-0 |
|---|---|
| Name: | 2-Aminoindole hydrochloride |
| Molecular Structure: | |
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|
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| Formula: | C8H8 N2 |
| Molecular Weight: | 132.165 |
| Synonyms: | 2-Aminoindole |
| Density: | 1.268±0.06 g/cm3(Predicted) |
| Melting Point: | 215-220 ºC dec. |
| Boiling Point: | 372.4°C at 760 mmHg |
| Flash Point: | 179°C |
| PSA: | 41.81000 |
| LogP: | 3.13330 |

(1H-indol-1-yl)(pyridin-2-yl)methanone


indoleamine

| Conditions | Yield |
|---|---|
| Stage #1: (1H-indol-1-yl)(pyridin-2-yl)methanone With tert.-butylnitrite; copper diacetate In 1,4-dioxane at 70℃; for 16h; Stage #2: With hydrazine hydrate; FeCl3/C In 1,4-dioxane; ethanol at 70℃; | 93% |

2-nitroindole


indoleamine

| Conditions | Yield |
|---|---|
| With sodium tetrahydroborate In water at 60℃; for 0.25h; Sonication; | 88% |

2-nitro-benzeneacetonitrile


indoleamine

| Conditions | Yield |
|---|---|
| With hydrogenchloride In ethanol at 30℃; for 3h; | 52% |

2-methyl-2-pyrrolidin-1-yl-propan-1-ol


5-Hydroxy-2-methyl-1H-indole-3-carboxylic acid benzyl ester


Toluene-2-sulfonyl chloride

A

indoleamine

B

2-Methyl-5-(2-methyl-2-pyrrolidin-1-yl-propoxy)-1H-indole-3-carboxylic acid benzyl ester

| Conditions | Yield |
|---|---|
| With potassium carbonate; triethylamine; trifluoroacetic acid In acetonitrile | A n/a B 5% |



(2-formylamino-phenyl)-acetonitrile


indoleamine

indoleamine


1-Phenyl-4,4,4-trifluorobutane-1,3-dione


2-phenyl-4-(trifluoromethyl)-9H-pyrido[2,3-b]indole

| Conditions | Yield |
|---|---|
| With acetic acid for 1h; Heating; | 89% |
| With acetic acid for 2h; Inert atmosphere; Reflux; regiospecific reaction; | 89% |

indoleamine


sodium 5,5,6,6,6-pentafluoro-2,4-hexanedione


2-methyl 4-(perfluoroethyl)-9H-pyrido[2,3-b]indole

| Conditions | Yield |
|---|---|
| With acetic acid for 2h; Inert atmosphere; Reflux; regiospecific reaction; | 87% |

indoleamine


1,1,1,5,5,5-hexafluoroacetylacetone


2,4-bis(trifluoromethyl)-9H-pyrido[2,3-b]indole

| Conditions | Yield |
|---|---|
| With acetic acid for 2h; Inert atmosphere; Reflux; regiospecific reaction; | 86% |

indoleamine


1-Chlor-1,1-difluor-3-benzoyl-aceton


4-(chlorodifluoromethyl)-2-phenyl-9H-pyrido[2,3-b]indole

| Conditions | Yield |
|---|---|
| With acetic acid for 2h; Inert atmosphere; Reflux; regiospecific reaction; | 85% |
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Molecular Structure of 2-Aminoindole hydrochloride (CAS NO.36946-70-0):

Molecular Formula: C8H9ClN2
Molecular Weight: 168.6235
Systematic Name: 1H-Indol-2-amine hydrochloride (1:1)
Synonyms of 2-Aminoindole hydrochloride (CAS NO.36946-70-0): 1H-Indol-2-amine hcl
CAS NO: 36946-70-0
Product Categories: Nitrogen cyclic compounds ; Indole Derivatives
Melting point: 215-220°C
Flash Point: 179 °C
Enthalpy of Vaporization: 63.17 kJ/mol
Boiling Point: 372.4 °C at 760 mmHg
Vapour Pressure: 6.6E-06 mmHg at 25°C