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| CAS No.: | 40283-46-3 |
|---|---|
| Name: | 2-AMINOTHIAZOLE-5-CARBOXYLIC ACID |
| Molecular Structure: | |
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|
|
| Formula: | C4H4N2O2S |
| Molecular Weight: | 144.154 |
| Synonyms: | 2-Amino-5-thiazolecarboxylicacid;NSC 239729; |
| Density: | 1.657 g/cm3 |
| Melting Point: | 214-216 °C |
| Boiling Point: | 415 °C at 760 mmHg |
| Flash Point: | 204.8 °C |
| Hazard Symbols: |
Xi
|
| PSA: | 104.45000 |
| LogP: | 1.00470 |

2-amino-thiazole-5-carboxylic acid ethyl ester


2-aminothiazole-5-carboxylic acid

| Conditions | Yield |
|---|---|
| With sodium hydroxide In tetrahydrofuran; water Reflux; | 86% |
| With sodium hydroxide | |
| With barium dihydroxide | |
| With potassium hydroxide In methanol |

methyl 2-aminothiazole-5-carboxylate


2-aminothiazole-5-carboxylic acid

| Conditions | Yield |
|---|---|
| With sodium hydroxide Ambient temperature; | 74% |

2-acetylamino-thiazole-5-carbonitrile


2-aminothiazole-5-carboxylic acid

| Conditions | Yield |
|---|---|
| With hydrogenchloride |

2-aminothiazole-5-carboxylic acid


acetic anhydride


2-(acetylamino)thiazole-5-carboxylic acid

| Conditions | Yield |
|---|---|
| With pyridine at 20 - 130℃; | 71% |

2-aminothiazole-5-carboxylic acid


5-fluoro-1,3-thiazol-2-amine hydrochloride

| Conditions | Yield |
|---|---|
| Stage #1: 2-aminothiazole-5-carboxylic acid With potassium phosphate In 1,4-dioxane; methanol; toluene at 20℃; for 2h; Stage #2: With 1-(chloromethyl)-4-fluoro-1,4-diazabicyclo[2.2.2]octane-1,4-diium tetrafluoroborate In 1,4-dioxane; methanol; toluene at 20℃; for 0.5h; Stage #3: With hydrogenchloride In 1,4-dioxane; methanol; toluene Product distribution / selectivity; | 69% |

| Conditions | Yield |
|---|---|
| In ethanol for 6h; Reflux; | 44% |


2-aminothiazole-5-carboxylic acid


dibenzylamine

| Conditions | Yield |
|---|---|
| Stage #1: 2-aminothiazole-5-carboxylic acid With 4-methyl-morpholine; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate In N,N-dimethyl-formamide at 0℃; for 0.5h; Stage #2: dibenzylamine In N,N-dimethyl-formamide at 20℃; | 41% |

2-aminothiazole-5-carboxylic acid


(aminomethyl)cyclopropane hydrochloride


N-cyclopropylmethyl-2-aminothiazole-5-carboxamide

| Conditions | Yield |
|---|---|
| With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; |

2-aminothiazole-5-carboxylic acid


1-cyclopentylethyl amine hydrochloride


N-(1-cyclopentylethyl)-2-aminothiazole-5-carboxamide

| Conditions | Yield |
|---|---|
| With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; |

2-aminothiazole-5-carboxylic acid


N-cyclopentylmethyl-2-aminothiazole-5-carboxamide

| Conditions | Yield |
|---|---|
| With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine In N,N-dimethyl-formamide at 20℃; |
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IUPAC Name: 2-Amino-1,3-thiazole-5-carboxylic acid
Systematic of 5-Thiazolecarboxylicacid, 2-amino- (CAS NO.40283-46-3): 2-Amino-5-thiazolecarboxylic acid ; 2-Aminothiazole-5-carboxylic acid ; 2-Aminothiazol-5-ylcarboxylic acid ; Rarechem al be 1263 ; 2-Amino-1,3-thiazole-5-carboxylic acid ; 2-Amino-1,3-thiazole-5-carboxylic acid 98%
CAS NO: 40283-46-3
Molecular Formula of 5-Thiazolecarboxylicacid, 2-amino- (CAS NO.40283-46-3): C4H4N2O2S
Molecular Weight: 144.1518
Molecular Structure:
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Melting Point: 214-216°C
ProductCategories: Amines ; blocks ; Carboxes ; Thiazoles
H bond acceptors: 4
H bond donors: 3
Freely Rotating Bonds: 1
Polar Surface Area: 70.67 Å2
Index of Refraction: 1.707
Molar Refractivity: 33.89 cm3
Molar Volume: 86.9 cm3
Surface Tension: 96.5 dyne/cm
Density of 5-Thiazolecarboxylicacid, 2-amino- (CAS NO.40283-46-3): 1.657 g/cm3
Flash Point: 204.8 °C
Enthalpy of Vaporization: 70.43 kJ/mol
Boiling Point: 415 °C at 760 mmHg
Vapour Pressure: 1.25E-07 mmHg at 25°C
Hazard Codes:
Xi
Hazard Note: Irritant/Keep Cold