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CAS No.: | 57-68-1 |
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Name: | Sulfamethazine |
Article Data: | 27 |
Molecular Structure: | |
Formula: | C12H14N4O2S |
Molecular Weight: | 278.335 |
Synonyms: | Sulfanilamide,N1-(4,6-dimethyl-2-pyrimidinyl)- (8CI);2-(4-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine;2-(p-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine;2-Sulfanilamido-4,6-dimethylpyrimidine;4-Amino-N-(2,6-dimethyl-4-pyrimidinyl)benzenesulfonamide;Azolmetazin;BN 2409;Calfspan;Calfspan Tablets;Diazil;Dimidin R;Kelametazine;Mermeth;N-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide;N1-(4,6-Dimethyl-2-pyrimidyl)sulfanilamide;NSC 67457;NSC 683529;Neasina;Neazina;Panazin;Pirmazin;Spanbolet;Sulfadimerazine;Sulfadimesin;Sulfadimethyldiazine;Sulfadimethylpyrimidine;Sulfadimezine;Sulfamethazine;Sulfamethiazine;Sulphadimethylpyrimidine;Sulphadimidine;Sulphamezathine;Sulphamidine;Sulphodimezine;Sustain III;Vertolan;Sulfadimethoxine;Sulfamethazine; |
EINECS: | 200-346-4 |
Density: | 1.392 g/cm3 |
Melting Point: | 197 °C |
Boiling Point: | 526.2 °C at 760 mmHg |
Flash Point: | 272.1 °C |
Solubility: | 150mg/100mL (29 °C) in water |
Appearance: | White to off-solid |
Hazard Symbols: | Xi |
Risk Codes: | 36/37/38 |
Safety: | 23-24/25-36-26 |
PSA: | 106.35000 |
LogP: | 3.21140 |
Conditions | Yield |
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With potassium carbonate |
(E)-4-(piperidino)pent-3-en-2-one
1-amino-4-({[amino(imino)methyl]amino}sulfonyl)benzene
sulfadimesine
N-(4,6-dimethyl-pyrimidin-2-yl)-4-nitro-benzenesulfonamide
sulfadimesine
Conditions | Yield |
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With hydrogenchloride; iron | |
With hydrogenchloride; iron |
Conditions | Yield |
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With sodium hydroxide | |
With calcium hydroxide |
[4-(4,6-dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-carbamic acid ethyl ester
sulfadimesine
Conditions | Yield |
---|---|
With potassium carbonate |
Conditions | Yield |
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anschliessendes Erhitzen mit <4,6-Dimethyl-pyrimidin-2-yl>-trimethyl-ammonium-chlorid; |
Conditions | Yield |
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Multi-step reaction with 2 steps 1: Na2CO3 2: aq. NaOH solution View Scheme | |
Multi-step reaction with 2 steps 1: K2CO3; toluene 2: K2CO3 View Scheme |
Conditions | Yield |
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Multi-step reaction with 2 steps 2: iron-powder; aq.-ethanolic HCl View Scheme | |
Multi-step reaction with 2 steps 2: aq. NaOH solution View Scheme |
1. | scu-rat LD50:2 g/kg ABMGAJ 27,141,71 | |||
2. | ipr-mus LD50:1060 mg/kg | AITEAT Archivum Immunologiae et Therapiae Experimentalis. 16 (1968),804. | ||
3. | ivn-mus LD50:1776 mg/kg | HBTXAC Handbook of Toxicology, Volumes I-V. 5 (1959),163. |