Products Categories
CAS No.: | 6310-09-4 |
---|---|
Name: | 2-ACETYL-5-CHLOROTHIOPHENE |
Article Data: | 18 |
Molecular Structure: | |
Formula: | C6H5 Cl O S |
Molecular Weight: | 160.624 |
Synonyms: | Ketone,5-chloro-2-thienyl methyl (6CI,7CI,8CI);1-(5-Chloro-2-thienyl)ethanone;1-(5-Chlorothiophen-2-yl)ethanone;2-Acetyl-5-chlorothiophene;2-Chloro-5-acetylthiophene;5-Chloro-2-acetylthiophene;NSC 43020; |
EINECS: | 228-630-3 |
Density: | 1.312g/cm3 |
Melting Point: |
46-49 °C(lit.) |
Boiling Point: |
117-118 °C17 mm Hg(lit.) |
Flash Point: | 227 °F |
Appearance: | white to light yellow crystal powder |
Risk Codes: | 20/21/22 |
Safety: | Experimental reproductive effects. A flammable liquid. When heated to decomposition it emits toxic vapors of SOx and Cl−. |
Transport Information: | UN 2811 |
PSA: | 45.31000 |
LogP: | 2.60410 |
5-chloro-2-(α-methoxyimino)ethylthiophene
2-acetyl-5-chlorothiophene
Conditions | Yield |
---|---|
With hydrogenchloride at 70℃; for 8h; | 96% |
Conditions | Yield |
---|---|
With ytterbium(III) triflate In nitromethane at 20℃; for 4h; Friedel-Crafts acylation; | 90% |
With zinc trifluoromethanesulfonate In nitromethane at 20℃; for 4h; Friedel-Crafts acylation; | 87% |
With tetrachloromethane; aluminium trichloride | |
With aluminium trichloride; Petroleum ether Behandeln des Reaktionsprodukts mit Wasser; | |
Stage #1: acetyl chloride With aluminum (III) chloride In tetrachloromethane at 0℃; for 0.333333h; Friedel Crafts Acylation; Stage #2: 2-thienyl chloride In tetrachloromethane at 0℃; for 1.58333h; Friedel Crafts Acylation; Stage #3: With hydrogenchloride; water In tetrachloromethane |
Conditions | Yield |
---|---|
With perchloric acid at 0 - 20℃; for 6.5h; | 81% |
activated clay at 45 - 55℃; for 73h; | 52% |
With phosphoric acid |
Conditions | Yield |
---|---|
With N,N,N-trimethylbenzenemethanaminium dichloroiodate; zinc(II) chloride In acetic acid at 70℃; for 24h; | A 69% B 7% |
With N,N,N-trimethylbenzenemethanaminium dichloroiodate; zinc(II) chloride In acetic acid at 70℃; for 24h; Product distribution; with different molar ratio; | A 47% B 22% |
With N,N,N-trimethylbenzenemethanaminium dichloroiodate; zinc(II) chloride In acetic acid at 70℃; for 24h; | A 47% B 22% |
2-thienyl chloride
acetic anhydride
trifluoroborane diethyl ether
A
2-acetyl-5-chlorothiophene
2-acetyl-5-chlorothiophene
Conditions | Yield |
---|---|
sodium hydroxide at 25℃; Rate constant; |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 81 percent / Na2CO3, AcOH / methanol; H2O / 2 h / Heating; pH 4.5 2: 62 percent / Fe, Cl2 / CHCl3 / 3 h / Heating 3: 96 percent / 25percent HCl / 8 h / 70 °C View Scheme | |
Multi-step reaction with 4 steps 1: 98 percent / NH2OH*HCl, Na2CO3, AcOH / methanol; H2O / 2 h / Heating 2: 95 percent / NaOH / dimethylformamide; H2O / 0.5 h / 10 °C 3: 62 percent / Fe, Cl2 / CHCl3 / 3 h / Heating 4: 96 percent / 25percent HCl / 8 h / 70 °C View Scheme |
2-acetylthiophene oxime
2-acetyl-5-chlorothiophene
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 95 percent / NaOH / dimethylformamide; H2O / 0.5 h / 10 °C 2: 62 percent / Fe, Cl2 / CHCl3 / 3 h / Heating 3: 96 percent / 25percent HCl / 8 h / 70 °C View Scheme |
2-(α-methoxyimino)ethylthiophene
2-acetyl-5-chlorothiophene
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 62 percent / Fe, Cl2 / CHCl3 / 3 h / Heating 2: 96 percent / 25percent HCl / 8 h / 70 °C View Scheme |
2-acetyl-5-chlorothiophene
Conditions | Yield |
---|---|
With hydrogenchloride |
What can I do for you?
Get Best Price
IUPAC Name: 1-(5-Chlorothiophen-2-yl)ethanone
Synonyms: 1-(5-Chloro-2-thienyl)ethan-1-one ; 1-(5-Chloro-thiophen-2-yl)-ethanone ; 2-Acetyl-5-chlorthiophen ; 2-Chloro-5-acetylthiophene ; 5-Chlor-2-acetyl thiophen ; 5-Chlor-2-acetylthiophen ; 5-Chloro-2-acetyl thiophen
The Molecular Formula of 5-Chlor-2-acetyl thiophen (6310-09-4):C6H5ClOS
The Molecular Weight of 5-Chlor-2-acetyl thiophen (6310-09-4) :160.6213g/mol
The Molecular Structure of 5-Chlor-2-acetyl thiophen (6310-09-4):
Index of Refraction: 1.559
Molar Refractivity: 39.56 cm3
Molar Volume: 122.3 cm3
Polarizability: 10-24cm3
Surface Tension: 41.9 dyne/cm
Density: 1.312 g/cm3
Flash Point: 108.3 °C
Enthalpy of Vaporization: 47 kJ/mol
Boiling Point: 233.3 °C at 760 mmHg
Vapour Pressure: 0.0562 mmHg at 25°C
5-Chlor-2-acetyl thiophen (6310-09-4) can be used in organic synthesis.
Experimental reproductive effects. A flammable liquid. When heated to decomposition it emits toxic vapors of SOx and Cl−.
Safety Statements: 24/25
S24/25: Avoid contact with skin and eyes
WGK Germany: 3
DOT Classification: 3; Label: Flammable Liquid