Products Categories
| CAS No.: | 72235-52-0 |
|---|---|
| Name: | 2,4-Difluorobenzylamine |
| Molecular Structure: | |
|
|
|
| Formula: | C7H7F2N |
| Molecular Weight: | 143.136 |
| Synonyms: | (2,4-Difluorophenyl)methanamine;2,4-Difluorobenzenemethanamine;[(2,4-Difluorophenyl)methyl]amine; |
| EINECS: | 276-502-0 |
| Density: | 1.214 g/cm3 |
| Melting Point: | 255-256 °C(Solv: N,N-dimethylformamide (68-12-2)) |
| Boiling Point: | 177.8 °C at 760 mmHg |
| Flash Point: | 68.3 °C |
| Appearance: | clear colorless to light yellow liquid |
| Hazard Symbols: |
 C
|
| Risk Codes: | 34 |
| Safety: | 26-27-36/37/39-45-25 |
| Transport Information: | UN 2735 8/PG 3 |
| PSA: | 26.02000 |
| LogP: | 2.12380 |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 894852-01-87-BROMO-2,2-DIMETHYL-2H-PYRIDO[3,2-B][1,4]OXAZIN-3(4H)-ONE
- 90221-55-92-bromo-5-methylbenzaldehyde
- 885590-99-82,3-DIFLUORO-4-IODOBENZALDEHYDE
- 72235-52-0
2,4-Difluoro-benzylamine
| Conditions | Yield |
|---|---|
| With hydrogenchloride In methanol; water for 6h; Reflux; | 90.8% |
- 3939-09-1
2,4-difluorobenzonitrile
- 72235-52-0
2,4-Difluoro-benzylamine
| Conditions | Yield |
|---|---|
| With ammonium hydroxide; hydrogen In water; isopropyl alcohol at 60 - 80℃; under 7500.75 Torr; Temperature; Reagent/catalyst; | 90% |
| With [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; 1,4-di(diphenylphosphino)-butane; iso-butanol; sodium hydroxide at 120℃; for 0.333333h; Inert atmosphere; | 75 %Chromat. |
- 372-18-9
1,3-Difluorobenzene
- 72235-52-0
2,4-Difluoro-benzylamine
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: hydrogen bromide; iron(III) chloride / 1,4-dioxane / 7 h / Reflux 2: 1,4-dioxane / 4 h / Reflux 3: hydrogenchloride / water; methanol / 6 h / Reflux View Scheme | |
| Multi-step reaction with 3 steps 1: hydrogenchloride; zinc(II) chloride / acetonitrile; water / 8 h / Reflux 2: toluene / 2 h / Reflux; Industrial scale 3: hydrogenchloride / water; isopropyl alcohol / 5 h / Reflux View Scheme | |
| Multi-step reaction with 4 steps 1.1: nitrobenzene / 2 h / 70 - 105 °C 2.1: ozone / chlorobenzene / 1.5 h / 0 °C 3.1: thionyl chloride / dichloromethane / 1 h / 50 °C 3.2: 1.5 h / 50 °C 4.1: sodium chloride; bromine / 2 h / 50 °C View Scheme |
- 452-07-3
2,4-difluorobenzyl chloride
- 72235-52-0
2,4-Difluoro-benzylamine
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: toluene / 2 h / Reflux; Industrial scale 2: hydrogenchloride / water; isopropyl alcohol / 5 h / Reflux View Scheme |
- 72235-52-0
2,4-Difluoro-benzylamine
| Conditions | Yield |
|---|---|
| With hydrogenchloride In water; isopropyl alcohol for 5h; Reflux; |
- 937397-44-9
{1-benzyl-3-[(3-fluoro-4-nitro-benzenesulfonyl)-isobutyl-amino]-2-hydroxy-propyl}-carbamic acid hexahydro-furo[2,3-b]furan-3-yl ester
- 72235-52-0
2,4-Difluoro-benzylamine
- 937721-16-9
(1-benzyl-3-{[3-(2,4-difluoro-benzylamino)-4-nitro-benzenesulfonyl]-isobutyl-amino}-2-hydroxy-propyl)-carbamic acid hexahydro-furo[2,3-b]furan-3-yl ester
| Conditions | Yield |
|---|---|
| In tetrahydrofuran for 18h; Heating / reflux; | 100% |
| Conditions | Yield |
|---|---|
| With triethylamine at 20℃; | 100% |
- 72235-52-0
2,4-Difluoro-benzylamine
- 556-61-6
methyl thioisocyanate
- 1400799-52-1
1-(2,4-difluorobenzyl)-3-methylthiourea
| Conditions | Yield |
|---|---|
| at 20℃; | 99% |
- 1357289-08-7
2,5-dimethyl 3-(benzyloxy)-1-(2,2-dimethoxyethyl)-4-oxo-1,4-dihydropyridine-2,5-dicarboxylate
- 72235-52-0
2,4-Difluoro-benzylamine
- 1229006-21-6
1-[2,2-bis(methyloxy)ethyl]-5-({[(2,4-difluorophenyl)methyl]amino}carbonyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylic acid methyl ester
| Conditions | Yield |
|---|---|
| With acetic acid In toluene at 90℃; for 7h; Reagent/catalyst; | 97% |
| With acetic acid In toluene at 90 - 95℃; Solvent; regioselective reaction; | 210 g |
- 72235-52-0
2,4-Difluoro-benzylamine
| Conditions | Yield |
|---|---|
| Stage #1: 5-(((tert-butoxycarbonyl)amino)methyl)-2-(3-(cyclopropylmethoxy)-4-methoxyphenyl)oxazole-4-carboxylic acid With 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0℃; for 0.5h; Stage #2: 2,4-Difluoro-benzylamine With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 12h; | 97% |
What can I do for you?
Get Best Price
Chemistry
Chemistry informtion about 2,4-Difluorobenzylamine (CAS NO.72235-52-0) is:
IUPAC Name: (2,4-Difluorophenyl)Methanamine
Synonyms: 2,4-Difluorobenzylamine ; Rarechem Al Bw 0282 ; 2,4-Difluorobenzylamine 97% ; 2,4-Difluorobenzylamine97% ; 2,4-Difluorobenzylamine Hydrochloride ; 2,4-Difluorobenzylamine, 98+% ; (2,4-Difluorophenyl)Methanamine ; Benzenemethanamine, 2,4-Difluoro-
MF: C7H7F2N
MW: 143.13
EINECS: 276-502-0
Density: 1.214 g/cm3
Flash Point: 79.4 °C
Boiling Point: 183.8 °C at 760 mmHg
Vapour Pressure: 0.756 mmHg at 25°C
Enthalpy of Vaporization: 42.01 kJ/mol
Refractive Index: n
Sensitive: Air Sensitive
BRN: 3539259
Following is the molecular structure of 2,4-Difluorobenzylamine (CAS NO.72235-52-0) is:
Safety Profile
Safty information about 2,4-Difluorobenzylamine (CAS NO.72235-52-0) :
Hazard Codes:
C: Corrosive
Risk Statements:
R34:Causes burns.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S27:Take off immediately all contaminated clothing.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S25:Avoid contact with eyes.
RIDADR: UN 2735 8/PG 3
WGK Germany: 3
Hazard Note: Corrosive
HazardClass: 8
PackingGroup: III
Specification
2,4-Difluorobenzylamine (CAS NO.72235-52-0) is a clear colorless to light yellow liquid.
First Aid Measures:
Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Skin: Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Eyes: Get medical aid immediately. Do not allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).
Handling and Storage:
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.
Handling: Wash thoroughly after handling. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Use only in a chemical fume hood. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.