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| CAS No.: | 751-94-0 |
|---|---|
| Name: | Sodium fusidate |
| Molecular Structure: | |
|
|
|
| Formula: | C31H47NaO6 |
| Molecular Weight: | 538.70 |
| Synonyms: | 16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid sodium salt; |
| EINECS: | 212-030-3 |
| Boiling Point: | 635.6 °C at 760 mmHg |
| Flash Point: | 197.6 °C |
| Solubility: | soluble in water |
| Appearance: | while crystalline power |
| Hazard Symbols: |
 Xn
|
| Risk Codes: | 22 |
| Safety: | 26-36 |
| PSA: | 106.89000 |
| LogP: | 4.33140 |
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Chemistry
Molecular structure of Fusidate Sodium (CAS NO.751-94-0) is:
Product Name: Fusidate Sodium
CAS Registry Number: 751-94-0
IUPAC Name: sodium(2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoate
Molecular Weight: 538.69105 [g/mol]
Molecular Formula: C31H47NaO6
H-Bond Donor: 2
H-Bond Acceptor: 6
EINECS: 212-030-3
storage temp.: 2-8°C
solubility: H2O: soluble
Flash Point: 197.6 °C
Enthalpy of Vaporization: 107.61 kJ/mol
Boiling Point: 635.6 °C at 760 mmHg
Vapour Pressure: 7.93E-19 mmHg at 25
Product Categories: Organics
Toxicity Data With Reference
| Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source | |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 170mg/kg (170mg/kg) | Lancet. Vol. 1, Pg. 928, 1962. | |
| mouse | LD50 | intravenous | 205mg/kg (205mg/kg) | Drugs in Japan Vol. 6, Pg. 675, 1982. | |
| mouse | LD50 | oral | 975mg/kg (975mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 1803, 1967. | |
| mouse | LD50 | subcutaneous | 313mg/kg (313mg/kg) | Lancet. Vol. 1, Pg. 928, 1962. | |
| rat | LD50 | subcutaneous | > 1gm/kg (1000mg/kg) | Drugs in Japan Vol. 6, Pg. 675, 1982. |
Safety Profile
Safty information about Fusidate Sodium (CAS NO.751-94-0) is:
Poison by intraperitoneal, subcutaneous, and intravenous routes. Used as an antibacterial agent. When heated to decomposition it emits toxic fumes of Na2O.
Hazard Codes: 
Xn,Xi
Risk Statements: 22-36/37/38
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: LV5775000
Specification
Fusidate Sodium , its cas register number is 751-94-0. It also can be called Fusidic acid sodium salt ; 16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid sodium salt .It is an antibiotic isolated from the fermentation broth of Fusidium coccineum. It acts by inhibiting translocation during protein synthesis.