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Basic Information
CAS No.: 79293-84-8
Name: N-(TERT-BUTYLDIMETHYLSILYL)PHTHALIMIDE
Molecular Structure:
Molecular Structure of 79293-84-8 (N-(TERT-BUTYLDIMETHYLSILYL)PHTHALIMIDE)
Formula: C14H19 N O2 Si
Molecular Weight: 261.396
Synonyms: N-(TERT-BUTYLDIMETHYLSILYL)PHTHALIMIDE;N-(T-BUTYLDIMETHYLSILYL)PHTHALIMIDE
Density: 1.09g/cm3
Melting Point: 115-119 °C(lit.)
Boiling Point: 336°C at 760 mmHg
Flash Point: 157°C
Safety:
WGK Germany 3
TSCA No
PSA: 37.38000
LogP: 3.22570
Synthetic route
136918-14-4

phthalimide

77086-38-5

ketene t-butyldimethylsilyl methyl acetal

79293-84-8

N-(tert-butyldimethylsilyl)phthalimide

Conditions
ConditionsYield
In acetonitrile at 60℃; for 0.25h;77%
136918-14-4

phthalimide

18162-48-6

tert-butyldimethylsilyl chloride

79293-84-8

N-(tert-butyldimethylsilyl)phthalimide

Conditions
ConditionsYield
With triethylamine In dichloromethane for 6h; Heating;71%
With triethylamine In dichloromethane at 20℃; for 4.5h;65%
10416-67-8

N-(trimethylsilyl)phthalimide

79293-84-8

N-(tert-butyldimethylsilyl)phthalimide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrahydrofuran / 20 °C
2: triethylamine / dichloromethane / 4.5 h / 20 °C
View Scheme
906096-91-1

3-(2-bromoethyl)-4-(phenylsulfonyl)-1,2,5-oxadiazole

79293-84-8

N-(tert-butyldimethylsilyl)phthalimide

906096-92-2

2-{2-[4-(phenylsulfonyl)-1,2,5-oxadiazol-3-yl]ethyl}-1H-isoindole-1,3(2H)-dione

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 3h; Heating;92%
79293-84-8

N-(tert-butyldimethylsilyl)phthalimide

203392-27-2

methyl 2-[fluoro(phenyl)methyl]acrylate

methyl 2-((1,3-dioxoisoindolin-2-yl)(phenyl)methyl)acrylate

Conditions
ConditionsYield
With 1,4-diaza-bicyclo[2.2.2]octane In dichloromethane at 25℃; regioselective reaction;90%
66197-72-6

diethyl (bromomethyl)phosphonate

79293-84-8

N-(tert-butyldimethylsilyl)phthalimide

33512-26-4

diethyl (phthalimidomethyl)phosphonate

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 12h; Heating;85%
5324-30-1

diethyl 2-bromoethylphosphonate

79293-84-8

N-(tert-butyldimethylsilyl)phthalimide

62514-90-3

[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)ethyl]phosphonic acid diethyl ester

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 8h; Heating;84%
79293-84-8

N-(tert-butyldimethylsilyl)phthalimide

13276-51-2

6-chloro-2-fluoro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine

A

9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-2-fluoro-6-phthalimido-9H-purine

B

9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-6-chloro-2-phthalimido-9H-purine

Conditions
ConditionsYield
With cesium fluoride In N,N-dimethyl-formamide at 20℃; for 24h;A 4%
B 84%
With 4 A molecular sieve; tetrabutyl ammonium fluoride In tetrahydrofuran; N,N-dimethyl-formamide at 20℃; for 24h;A 19%
B 57%
1186-10-3

diethyl 3-(bromopropyl)phosphonic acid

79293-84-8

N-(tert-butyldimethylsilyl)phthalimide

107257-50-1

[3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)propyl]phosphonic acid diethyl ester

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran for 8h; Heating;79%
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    High purity Application:Pharmaceutical intermediates, Material synthesis and analyzing the expectant ingredients

    Novachemistry offers a broad range of specialty chemicals and customized synthesis services to a range of pharmaceutical, agrochemical and biochemical industries. Novachemistry has

  • NovaChemistry

    United Kingdom  |  Contact Details

    Business Type:Trading Company

    Tel:+44 (0)208 191 7890

    Address:Unit11, Ark Business Centre, Gorden Road, Loughborough, United Kingdom

       Inquiry Now

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