CAS No.86220-45-3,cadystin Suppliers

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Basic Information

Molecular Structure:
CAS No.:	86220-45-3
Name:	cadystin
Article Data:	5

Formula:	C26H41 N7 O14 S3
Molecular Weight:	771.848
Synonyms:	CadystinA (reduced); Phytochelatin 3
Density:	1.484g/cm³
Boiling Point:	1375.8°C at 760 mmHg
Flash Point:	785.8°C
PSA:	466.22000
LogP:	-1.63200

Synthetic route

: 131574-49-7
Boc-<γ-Glu(OBzl)-Cys(MBzl)>3-Gly-OBzl

: 86220-45-3
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin A <1>)

Conditions

Conditions	Yield
With methyl-phenyl-thioether; hydrogen fluoride; 3-methyl-phenol at 0℃; for 1h;	82.8%

: 138901-84-5
H-<γ-Glu-Cys(StBu)>3-Gly-OH

: 86220-45-3
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin A <1>)

Conditions

Conditions	Yield
With ammonium acetate; 2-hydroxyethanethiol for 2h; Ambient temperature;	66%

: 95014-76-9
Tr-L-Glu-OBn>

: 86220-45-3
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin A <1>)

Conditions

Conditions	Yield
With hydrogen fluoride; ethane-1,2-dithiol; methoxybenzene at 0℃; for 1h;	40%
With hydrogen fluoride

: 70-18-8
GLUTATHIONE

A: 636-58-8
N-L-γ-glutamyl-L-cysteine

B: 86220-45-3
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin A <1>)

C: 95014-75-8
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin B <2>)

D: 100922-53-0
(γ-Glu-Cys)2

E: 118433-03-7
(γ-Glu-Cys)3

Conditions

Conditions	Yield
In water at 37℃; for 4h; transformation by carboxypeptidase Y; pH 9.7;

...Expand

: 138901-82-3
Nps-<γ-Glu(α-OtBu)-Cys(StBu)>3-Gly-OtBu

: 86220-45-3
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin A <1>)

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 2: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature 3: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature View Scheme

: 138923-96-3
H-γ-Glu(α-OtBu)-Cys(StBu)-Gly-OtBu

: 86220-45-3
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin A <1>)

Conditions

Conditions	Yield
Multi-step reaction with 6 steps 1: 82 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 2: 90 percent / methanolic 0.75 N HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 3: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 4: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 5: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature 6: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature View Scheme

Yield

Multi-step reaction with 6 steps
1: 82 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h
2: 90 percent / methanolic 0.75 N HCl, 2-methylindole / dioxane / 1 h / Ambient temperature
3: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h
4: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature
5: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature
6: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature
View Scheme

: 138901-88-9
Nps-Glu(OSu)-OtBu

: 86220-45-3
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin A <1>)

Conditions

Conditions	Yield
Multi-step reaction with 9 steps 1: 94 percent / 1N NaOH, NaHCO3 / dioxane; H2O / 12 h / Ambient temperature 2: 84 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 3: 89 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 4: 82 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 5: 90 percent / methanolic 0.75 N HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 6: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 7: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 8: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature 9: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature View Scheme
Multi-step reaction with 7 steps 1: 94 percent / 1N NaOH, NaHCO3 / dioxane; H2O / 12 h / Ambient temperature 2: 82 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 3: 90 percent / methanolic 0.75 N HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 4: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 5: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 6: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature 7: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature View Scheme

Yield

Multi-step reaction with 9 steps
1: 94 percent / 1N NaOH, NaHCO3 / dioxane; H2O / 12 h / Ambient temperature
2: 84 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h
3: 89 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature
4: 82 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h
5: 90 percent / methanolic 0.75 N HCl, 2-methylindole / dioxane / 1 h / Ambient temperature
6: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h
7: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature
8: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature
9: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature
View Scheme

Multi-step reaction with 7 steps
1: 94 percent / 1N NaOH, NaHCO3 / dioxane; H2O / 12 h / Ambient temperature
2: 82 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h
3: 90 percent / methanolic 0.75 N HCl, 2-methylindole / dioxane / 1 h / Ambient temperature
4: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h
5: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature
6: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature
7: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature
View Scheme

: 138901-78-7
Nps-γ-Glu(α-OtBu)-Cys(StBu)-OH

: 86220-45-3
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin A <1>)

Conditions

Conditions	Yield
Multi-step reaction with 8 steps 1: 84 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 2: 89 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 3: 82 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 4: 90 percent / methanolic 0.75 N HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 5: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 6: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 7: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature 8: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature View Scheme
Multi-step reaction with 6 steps 1: 82 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 2: 90 percent / methanolic 0.75 N HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 3: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 4: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 5: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature 6: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature View Scheme
Multi-step reaction with 4 steps 1: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 2: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 3: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature 4: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature View Scheme

: 138923-95-2
Nps-γ-Glu(α-OtBu)-Cys(StBu)-Gly-OtBu

: 86220-45-3
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin A <1>)

Conditions

Conditions	Yield
Multi-step reaction with 7 steps 1: 89 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 2: 82 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 3: 90 percent / methanolic 0.75 N HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 4: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 5: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 6: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature 7: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature View Scheme

Yield

Multi-step reaction with 7 steps
1: 89 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature
2: 82 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h
3: 90 percent / methanolic 0.75 N HCl, 2-methylindole / dioxane / 1 h / Ambient temperature
4: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h
5: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature
6: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature
7: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature
View Scheme

: 138901-80-1
H-<γ-Glu(α-OtBu)-Cys(StBu)>2-Gly-OtBu

: 86220-45-3
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin A <1>)

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 79 percent / HOBt, N-ethylmorpholine, DCCI / tetrahydrofuran / 1) 0 deg C, 1 h, 2) r.t., 1 h 2: 80 percent / 0.75 N methanolic HCl, 2-methylindole / dioxane / 1 h / Ambient temperature 3: 75 percent / TFA, ethyl methyl sulfide / 2 h / Ambient temperature 4: 66 percent / 2-mercaptoethanol, 0.1 M ammonium acetate / 2 h / Ambient temperature View Scheme

Casno:
86220-45-3
cadystin
Min.Order: 1 Kilogram
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86220-45-3
Glycine, L-g-glutamyl-L-cysteinyl-L-g-glutamyl-L-cysteinyl-L-g-glutamyl-L-cysteinyl-
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86220-45-3
Glycine, L-g-glutamyl-L-cysteinyl-L-g-glutamyl-L-cysteinyl-L-g-glutamyl-L-cysteinyl-
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Hubei Jiutian Bio-medical Technology CO.,Ltd, which is professional in research and sale high techology.The company located in Wuhan, We insist on the concept of "technology first,
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Casno:
86220-45-3
H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin A (1))
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Casno:
86220-45-3
cadystin
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FOB Price: USD $ 0.0-0.0
High purity, high success rate, short cycle and moderate priceAppearance:White powder solid Storage:Negative 20 degrees Celsius Package:5mg, 10mg 100mg, 1gram Application:Applied to various scientific research
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